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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

#PeopleOfKovsies brimming with positivity
2016-12-26

Kovsies both young and old, whether they are currently studying or have already graduated, abound in positive energy. Striving to harness this positivity, the #PeopleOfKovsies campaign was born. Over the past three years, this campaign has garnered a collection of photographs and quotable quotes from visitors, staff, students, and alumni that showcases the feeling that only a Kovsie knows.

The process is simple: Staff photographers approach people on campus and ask whether they are willing to pose for a photo. How they do this is up to the individual’s favourite style: pouting, looking serious, pointing, or just smiling. Participants then also have the opportunity to share a brief message with the Kovsie community, whether it is just how they feel at that particular moment, what it means to them to be a Kovsie, or how they picture that indescribable Kovsie feeling. These photographs, along with their captions, are shared on our social media platforms, and, in some cases, used on campus billboards or in our publications.

Description: Retha Hill Tags: Retha Hill

“I loved being a Kovsie, because my fellow Kovsies were more than just friends   they were like
FAMILY.” - Retha Hill

Description: Keamogetswe Nnyane Tags: Keamogetswe Nnyane

“I get to enrich my community through the diversity and exposure I received as a Kovsie.
To help uplift those who can’t do the same for themselves.” - Keamogetswe Nnyane

Description: Byron Wegger Tags: Byron Wegger

“The gateway that opened my mind to different ideas as well as giving me opportunities
through sport and academics I never would have experienced anywhere else.” - Byron Wegger

Description: Tamie Mbombo_PeopleOfKovsies Tags: Tamie Mbombo

“They have succeeded in creating the conditions wherein students from disadvantaged
backgrounds can be brought to the starting line of a race that many are unaware is even
being run.”-  Tamie Mbombo

Description: Lerothodi Molete Tags: Lerothodi Molete

“It means being an agent of change. Also equipping me with skills and exposure to be the
change I want to see in the world.” - Lerothodi Molete

Description: Lebogang Kotsi Tags: Lebogang Kotsi

"To be a Kovsie means being in a multi-racial learning institution and striving to be a great
leader in the future." - Lebogang Kotsi




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