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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

First Black Rag Queen wants to give voice to voiceless
2017-02-22

Description: Coronation ball 2017 Tags: Coronation ball 2017

The winners of the 2017 Amanzi Coronation
ball are, from the left: Devina Harry,
Second Princess; Kgomotso Sebusi,
First Princess; Prudence Mahlaba, Rag Queen;
Suhail Peerbhai, Mr Rag; Jordan Nadasen,
First Runner-up; and Mohlale Matlala,
Second Runner-up.
Photo: Gerhardus Bosch


“It is true what they say about your purpose driving you towards your goal. The ride to eventually becoming the first black RAG Queen was motivated by a pure desire in my heart to help other people.”

This is the moving words of Prudence Mahlaba, who was crowned Rag Queen at the Amanzi Coronation Ball on Friday 17 February 2017. Suhail Peerbhai, a second-year BCom Economics student, was crowned Mr Rag 2017.

Giving a voice to the voiceless

Mahlaba says she wants to make a positive impact, “not only on the less fortunate, but also on the voiceless.” The fourth-year LLB student strives to adhere to the vision of the acronym RAG (Receive and Give). RAG is mainly about a good cause in order to make a difference.
“It is beauty with a purpose, practising what you preach, and doing unto others what you want them to do unto you,” Mahlaba said.

It was a night of glitz and glamour as the finalists made a last bid for the sought-after titles at the prestigious event held at the Student Church on the Bloemfontein Campus of the University of the Free State.

Role provide foundation for change
“Becoming Mr Rag is an exceptional feeling; however, this role entails much more responsibility,” Peerbhai said. “At a time like this, it has given me a solid foundation to make a difference in communities that are less fortunate.”

His advice to future participants in the contest is, “to go for it, since it entails the most life-changing challenges students in our era can face. No classroom teachings can provide you with the same values and experiences.”

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