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07 January 2018
Photo Charl Devenish
Dr Anneke van der Spoel van Dijk is invested in contributing
to the global effort of stopping TB by 2035.
The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB).
She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB).
Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.
Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”
Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”
As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.
NASA Deep Space Navigation engineer presents at Naval Hill Planetarium
2017-03-30
From the left: Chris du Plessis; US Consulate, Johannesburg,
Prof Petrus Meintjes; Dept of Physics UFS, Christopher Jacobs;
NASA, and Anthony Deaton; US Consulate Johannesburg.
Photo: Rulanzen Martin
The University of the Free State (UFS) hosted NASA Deep Space engineer Christopher Jacobs on 27 March 2017 at the Bloemfontein Campus. The engagement was hosted by Prof Matie Hoffman of the Department of Physics and the Department of Institutional Advancement, in collaboration with the US Consulate General in Johannesburg.
Jacobs is stationed at NASA’s Jet Propulsion Laboratory (JPL) at the California Institute of Technology and has served as the Reference Frame Calibration task manager for 25 years. In this role he has been responsible for delivering the reference frames used to navigate NASA missions such as the Mars Science Laboratory to planetary targets.
His visit to the UFS included a presentation to the Department of Astrophysics at the Faculty of Natural and Agricultural Sciences and at the Naval Hill Planetarium in Bloemfontein where he spoke on Stellar GPS: Navigating the Solar System. He also spoke about the latest research and developments at NASA in Astrometry. The visit will establish and develop shared interests and possible collaboration with UFS and other institutions of interest in the country. “South Africa, because of its well-placed geographic location in the southern hemisphere, holds a lot of answers to astronomy,” Jacobs said.
He has an active interest in professional and public education, and outreach, having given public lectures around the world. “Astronomy brings people together and is a point of common interest that is key in solving environmental and geographical challenges such as climate change, therefore global cooperation is important,” he said.
Prof Hoffman welcomed the initiative by the US Consulate and the possible outcomes of joint efforts to position the UFS as a key partner in South Africa on NASA’s astronomy projects. In the coming weeks Jacobs will speak at high schools in Gauteng including the Mae Jemison US Science Reading Room in Mamelodi, Pretoria, a centre that is focused on promoting science education.