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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

FS Premiers Documentary Film On Basotho King Moshoeshoe
2004-10-06

The University of the Free State (UFS) will premiere a documentary film on the legacy of King Moshoeshoe, Basotho leader of the nineteenth century for his role in nation-building and reconciliation on Wednesday 13 October 2004.

The hour-long documentary film, produced by the well-known journalist Mr Max du Preez, was commissioned by the UFS as part of its centenary celebrations.

“To us this film is a practical demonstration of the UFS’s commitment to the continued transformation of the campus, and its commitment to reconciliation and nation-building. It is seen as a contribution to one of the UFS’s key strategic priorities for this year, namely diversity, equity and redress,” says Prof Frederick Fourie, Rector and Vice-Chancellor of the UFS.

“Through these priorities, the UFS commits itself to developing a shared appreciation of the history of this country and to contribute to the establishment of the Free State Province as a model of reconciliation and nation building,” says Prof Fourie.

“King Moshoeshoe was a great African statesman and leader. He was born in this region of the country, but his influence and legacy extends way beyond the borders of the Free State, Lesotho and even way beyond the borders of South Africa,” says Prof Fourie.

Earlier this year the UFS launched a project to honor King Moshoeshoe. The project included among others the production of this documentary film, the possible presentation of an annual Moshoeshoe memorial lecture that will focus on African leadership, nation-building and reconciliation and PhD-level research into the life and legacy of King Moshoeshoe and a literary anthology including prose and poetry.

According to Prof Fourie the project will enable the UFS to give real meaning to words such as reconciliation, respect for the diversity of our languages and cultures, and the unity South Africans seek to build as a democratic nation through such diversity.

The documentary film on King Moshoeshoe will be screened on SABC 2 later this year.

Media release
Issued by: Lacea Loader
Media Representative
Tel: (051) 401-2584
Cell: 083 645 2454
E-mail: loaderl.stg@mail.uovs.ac.za
6 October 2004

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