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07 January 2018
Photo Charl Devenish
Dr Anneke van der Spoel van Dijk is invested in contributing
to the global effort of stopping TB by 2035.
The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB).
She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB).
Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.
Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”
Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”
As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.
Young academic receives BRICS research funding
2017-04-13
Dr Thulisile Mphambukeli and Dr Victor Okorie
from the Department of Urban and Regional Planning
at the University of the Free State.
Photo: Rulanzen Martin
“It means a lot to me, as I am a young academic embarking on my postdoctoral research project. To be able to lead a team of researchers from various research institutions in South Africa is humbling.” This is what Dr Thulisile Mphambukeli had to say on being awarded a research grant by the South African BRICS Think Tank.
The think tank, in collaboration with the National Institute for the Humanities and Social Sciences (NIHSS), awarded the lecturer in Urban and Regional Planning at the University of the Free State (UFS) R150 000. She will spearhead a research project between BRICS (Brazil, Russia, India, China, and South Africa) universities. “They have awarded me a three-month grant to facilitate a process of combining various research projects under the BRICS Academic Cluster,” Dr Mphambukeli said.
Platform provides collaboration
“The academic cluster provides a platform for researchers and academics to engage in ongoing collaboration,” she said. The grant will enable her and her research partner, Dr Victor Okorie, postdoctoral fellow in the Department of Urban and Regional Planning at the UFS, to put together a research proposal to be submitted at the end of May 2017. If successful, her team will conduct a research study across BRICS countries over a period of three years. It will be done in collaboration with various South African universities, who will form a team to collaborate with researchers from BRICS universities.
Great accomplishment for UFS
“The funds we have received are quite a great accomplishment for the UFS and our department,” Dr Okorie said. The UFS has become a force to be reckoned with when it comes to emerging issues in BRICS politics and policies. “Our project looks at the provision of ecosystems, agriculture, and security and the UFS was chosen as the host institution.”