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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Student makes SA academic history
2007-11-04

Pulane Mahloka, a final-year B.Sc. (Quantity Surveying) student at the University of the Free State (UFS), has made academic history by becoming the first black student to be awarded a gold medal by the Association of South African Quantity Surveyors (ASAQS).

She is the fourteenth UFS student since 1970 to receive this accolade, and is only the sixth female student of the UFS to attain this honour.

According to the modest 23-year-old Ms Mahloka, her academic success attests to the quality of training the University of the Free State is providing.

“I did not in my wildest dreams ever imagine that I could be selected as the winner. I feel truly humbled and grateful to be counted amongst the achievers in my field of study,” said Ms Mahloka.

By smashing through the proverbial glass ceiling, Ms Mahloka hopes that she can inspire black students all over the country, particularly those from previously disadvantaged backgrounds, so that they can realise that all is not gloomy.

Her advice to fellow students is: “There is little you can do about where you come from. Do not be ashamed, but work hard to develop yourself. Do not confine yourself by the fact that you were never exposed to certain equipment and books. Now that you have made it to university, it is your chance to work hard and make something out of your life.”

Ms Mahloka, who hails from Maseru in Lesotho, has been a star academic performer since her first year in 2003, when she received an award for the best first-year student.

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt.stg@mail.ufs.ac.za
2 November 2007
 

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