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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Boyden observatory celebrates its achievements
2004-10-05

The red carpet will be rolled out and champagne glasses filled tonight when the Boyden Observatory outside Bloemfontein will launch the first phase of the new science centre.

This phase, which was completed earlier this year, consists of a new auditorium, reception area and paths which connect educational visiting points on the Boyden terrain.

“Over the past two years the Boyden Observatory has been re-sited as a research, educational and public facility. The new facilities are now being utilised for educational and public programmes. The 1,5m Boyden telescope has also recently been upgraded and is used for research purposes,” says Dr Matie Hoffman from the University of the Free State’s (UFS) Department of Physics, who is responsible for the management of the centre.

“The Boyden Observatory is a unique facility of the UFS - we are one of the few universities in the world who has its own observatory,” says Dr Hoffman.

“The main purpose of the science centre is to create enthusiasm for science amongst the public. The centre also has a great educational function and focuses specifically on the improvement of the quality of science education in the Free State,” says Dr Hoffman.

Fund-raising for the planned second phase of the science centre, which will consist of interactive in- and outside exhibition areas, will also start tonight. “After the completion of the second phase the Boyden Observatory will probably become the most accessible and public-friendly observatory in the country and a great asset for the Free State Province,” says Dr Hoffman.

A small robotic telescope, which will be controlled from the University College Dublin in Ireland, will also be installed at the Boyden Observatory this year.

“Just as this year is a significant one for the UFS with its centenary celebrations, so it is also a significant one for the Boyden Observatory. The Harvard University in the United States of America started with the construction of the original 1,5 m telescope in its original form 100 years ago, the telescope was put in place at Boyden 70 years ago and Mr Uriah Boyden – the person who donated the money with which the Boyden Observatory was constructed, was born 200 years ago,” says Dr Hoffman.

The first phase of the science centre was built with funds sponsored by the AngloGold Fund, the Shuttleworth Foundation, the Charl van der Merwe Trust and the Lila Theron Trust. Donations from the Friends of Boyden Observatory and other individuals also contributed to the success of the project.

Those who are interested in educational tours of the science centre can contact Dr Hoffman at (051) 401-2322.

Media release
Issued by: Lacea Loader
Media Representative
Tel: (051) 401-2584
Cell: 083 645 2454
E-mail: loaderl.stg@mail.uovs.ac.za
5 October 2004

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