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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Suspect in theft of computer equipment arrested
2007-11-16

A suspect, who may be involved in the recent theft of computer equipment from buildings on the Bloemfontein campus of the University of the Free State (UFS), has been arrested.

On 13 November 2007 an alarm in the Agriculture Building on the Main Campus of the UFS was activated. Protection Services reacted to the alarm and the person, who tried to run away, was pursued and later arrested.

The suspect was handed to the South African Police Service (SAPS). Currently SAPS is conducting an intensive investigation in co-operation with Protection Services at the UFS.

“The extent of the investigation goes beyond this single case for which the captive was arrested,” said Mr Willie Frankim, Manager: Protection Services at the UFS.

Meanwhile, the UFS’s Safety Committee has decided on a number of measures to heighten security on campus, including:

  • Patrols between buildings are to be intensified.
  • Vehicles leaving the campus will be searched. This is being done on an ad hoc basis at all the gates.

According to Mr Frankim the university is also looking at extending the alarm system and measures to secure buildings on campus.
He said: “The above will not happen overnight. We request all staff members and students to give their co-operation and to be more security conscious by:

  • Giving their co-operation at the gates when their vehicle is searched,
  • To ensure that the windows of your office and building are closed,
  • To lock office doors when you leave the office, even if it is for a short while,
  • Not to leave your office unattended when there are strangers,
  • to report suspicious persons as soon as possible to Protection Services,
  • To ensure that valuable articles (laptops and cell phones) are locked away,
  • To ensure the safekeeping of keys (not in drawers or on top of a door frame), and
  • Determine who has access to a building and question anybody unknown.”

Contact Protection Services at any of the following numbers:

Duty room: O51-4012634 / 051-4012911

Mr Aggrey Litseho (investigation officer): 051-4013225 / 0836347919 /
Short cell phone x6060

Mr Willie Frankim (manager): 051 401 3438 / 0828831760/
Short cell phone x6000

“We can only combat crime if everybody is aware of their environment, everybody adheres to the basic rules and co-operates with Protection Services,” said Mr Frankim.

Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
15 November 2007
 

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