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Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Research grant holder first to be graded at UFS in NRF’s Thuthuka Programme
2007-11-17

 

In the picture, from the left are: Ms Gudrun Schirge (National Research Foundation), Mr Nico Benson (Directorate Research Development at the UFS), Prof Heidi Hudson (Department of Political Science at the UFS) and Dr Annelize Venter (Co-ordinator of the Thuthuka Programme at the UFS)
Photo: Mangaliso Radebe

 

Research grant holder first to be graded at UFS in NRF’s Thuthuka Programme

Prof. Heidi Hudson, Departmental Chairperson at the University of the Free State's (UFS) Department of Political Science, recently received a C1 grading from the National Research Foundation (NRF).

With this grading she became the first researcher and grant holder in the Thuthuka Programme for young researchers at the UFS to be graded by the NRF.

“The Thuthuka Programme is a capacity building initiative from the NRF which prepares young researchers for grading and provides them with a good grounding for research,” said Dr Annelize Venter, researcher at the UFS Research Development Directorate and co-ordinator of the Thuthuka Programme.

According to Dr Venter, the UFS currently has 44 researchers who receive funding from the Thuthuka Programme for their postgraduate studies. The results of possible entrants to the programme in 2008 are awaited.

”The UFS also received ten researchers additional to the current 69 who have a valid evaluation status. The results of an additional 11 applications are also awaited. Some of these are first applications,” said Dr Venter.

Over and above the grant holders in the Thuthuka Programme, any researcher can apply to be evaluated by the NRF’s Evaluation Centre. The evaluation status of a researcher serves as the norm determinator and the quality of research at a university is measured according to this.

Ms Gudrun Schirge from the NRF presented a workshop today at the UFS to researchers who wanted to apply for grading and evaluation.
Researchers who wished to apply for the re-evaluation of their current evaluation status also attended the workshop.

Ms Schirge was one of the founders of the evaluation system and has been a manager at the Evaluation Centre for the past 20 years. She will be retiring this year and will be involved with the centre on a part-time basis.

Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
16 November 2007
 

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