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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Five mega projects to help reposition the UFS
2008-02-01

The University of the Free State (UFS) today announced that it will focus on five mega-projects to help reposition the UFS in the next five years as one of South Africa’s leading universities that is successfully managing excellence and diversity.

Speaking at the official opening of the university today, the Rector and Vice-Chancellor, Prof. Frederick Fourie, identified the five mega projects as:

  • The successful implementation of strategic academic clusters to focus the teaching and research expertise of the UFS.
  • The development and implementation of new models of teaching and learning.
  • Finding new sources of income (including third-stream income) to minimise dependence on government subsidies and tuition fees.
  • Creating a new institutional culture for the university by finalising the Institutional Charter.
  • The ongoing transformation of the UFS in all its dimensions.

According to Prof. Fourie, the strategic clusters – initiated in 2006 – are a very important initiative which is aimed at making the UFS a world leader in six broad areas. The focus of the six clusters has now been determined. These clusters are not just research based, but will include postgraduate programmes and filter down to undergraduate learning programmes and curricula.

He also indicated that other research at the UFS will continue to be supported and funded as before.

The second project, to establish a new teaching and learning model, is meant to address current success rates which indicate the need for this issue to receive a high priority.

New income streams to enable higher levels of financial sustainability is the third project, especially in view of dwindling government subsidies and limits on student numbers. This is necessary to fund sustained higher levels of investment in the quality of academic activities and in the necessary capacity and facilities.

Prof. Fourie said the fourth project regarding institutional culture is an ongoing effort to create a sense of belonging for all staff and students at the UFS through the adoption of an Institutional Charter for the university.

“What the draft Charter does – in addition to describing overarching values espoused by the institution and its people – is to describe the outlines and constitutive principles of the ‘post-redress’ UFS,” said Prof. Fourie.

The Charter – initially launched in 2007 – is and remains a critical element of guiding transformation effectively and speedily towards a widely-accepted goal. It is a critical element of the “social sustainability and robustness” of a new UFS, especially in tumultuous political times.

The fifth project is the Transformation Plan, launched in 2007. “We simply must pursue this plan diligently, given our commitment to comprehensive and deep transformation, and to best practice transformation. All universities will have to face up to the challenge of transformation and the UFS can break new ground, as it did in the past by managing transformation innovatively and creating a campus where all can find their rightful place,” said Prof. Fourie.

Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
1 February 2008
 

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