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07 January 2018
Photo Charl Devenish
Dr Anneke van der Spoel van Dijk is invested in contributing
to the global effort of stopping TB by 2035.
The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB).
She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB).
Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.
Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”
Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”
As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.
Famous mineralogists visit UFS Geology
2017-04-25
From the left: Prof Marian Tredoux, Associate
Professor at the UFS Department of Geology;
Prof Giorgio Garuti; from the University of Leoben,
Dr Federica Zaccarini, also from the
University of Leoben and Dr Freddie Roelofse,
Head of the Department of Geology at the UFS.
Photo: Rulanzen Martin
Years of academic friendship and collaboration is what makes Prof Giorgio Garuti and Dr Federica Zaccarini return to the University of the Free State (UFS) every so often.
The world-renowned academic duo from the University of Leoben in Austria were guest lecturers at the UFS Department of Geology. “We are here because we have known Professor Marian Tredoux and the Geology Department, for a long time. We are really happy to be here, and to be given the opportunity to present talks,” said Dr Zaccarini. The two are experts in platinum-group element mineralogy and each has given their surname to minerals namely, the Garutiite and Zaccariniite minerals.
Visit great advantage for research
They are acclaimed experts on very small minerals (smaller than a hundredth of a millimetre) with emphasis on platinum group elements in chrome-rich rocks. “Their visit is a great advantage for us. We also conduct research on these minerals and can learn from them,” said Prof Marian Tredoux, affiliated researcher at the Department of Geology.
Dr Zaccarini gave a lecture on Chromitites, and associated platinum-group elements, in ophiolites on Wednesday 5 April 2017 and Dr Garuti presented a lecture on Uralian-Alaskan complexes: a puzzling source of platinum, on Thursday 6 April 2017. During the talks they examined the association of the platinum-group minerals with chromite, rather than sulphide, and how this association can lead to the formation of unusual platinum-group element ores.
Collaboration on various academic papers
They and Prof Tredoux have collaborated on various research articles over the past four years, which have been published in various important international scientific journals. “These journals play an important role in calculating the H-scale which measures how important a researcher’s work is on an international scale,” said Prof Tredoux.