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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Prof Steyn to receive Jan H Marais Prize in Stellenbosch
2017-05-09

Description: Prof Jaap Steyn  Tags: Prof Jaap Steyn

Prof Jaap Steyn, who started his career as
journalist at Volksblad, later entered the academy,
and was a professor at the University of the
Free State for many years.
Photo: Marthie Kemp

Although Prof Jaap Steyn will be honoured officially for his contribution to Afrikaans as an academic language at the end of this month, he only became aware of his nomination after he had won the award.

According to this research fellow in the Department of Afrikaans and Dutch, German and French at the University of the Free State (UFS), he is grateful for the recognition. He has recently been awarded the Jan H Marais Prize for his outstanding contribution to Afrikaans.

Former Kovsie honoured together with Prof Jan van der Watt
According to a statement by the South African Academy for Science and Arts, the award was jointly made to Prof Steyn, who is probably the best-known South African language historian, and Prof Jan van der Watt van Nijmegen from the Netherlands. The prize money of R500 000, which they will share, will be presented in Stellenbosch on 30 May 2017.

Prof Steyn is a former Kovsie, who was a research professor at the UFS from 1985 to 1997, and at the age of 78 is still a research fellow. “After the announcement of the prize, I learnt that I was nominated by two of my colleagues,” he says.

His most difficult work was probably also his best

Over the past 50 years several of his publications, biographies, and books have seen the light. He believes that nothing one does is perfect. His most difficult work was the biography of NP van Wyk Louw. “It was probably also my best work,” he says. “The book I enjoyed working on most, was the biography of the author MER, or ME Rothmann.”

Prof Steyn has also received awards such as the Stals Prize, the Louis Hiemstra Prize, the NP van Wyk Louw medal, and honorary membership from the South African Academy for Science and Arts.

He says the staff in the Department of Afrikaans and Dutch, German and French are very friendly and helpful to still render him assistance as a research fellow.


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