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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS acknowledge 53 for long service
2004-11-03

Long service awards for 35 years: Mrs. Christa du Plessis, Centre for Higher Education studies and Development, mnr. John Moorosi, Soil- and Crop- and Climate Sciences , prof. Frederick Fourie, rector, prof. Jopie Botha, Institute for Groundwater Studies, me. Susan Reineke, Plant Sciences, Dr. Sarie van Vuuren of Sociology and me. Aletta de Klerk, Kovsie Sport.

Fifty three personnel members received long service awards in the centenary year of the university for respectively 35 years of service and 25 years of service.

Prof. Frederick Fourie, Rector, said to the recipients of the long service awards: “In a year in which the writing of history of the UFS took a prominent place in the Centenary celebrations and in which one relived the past hundred years, the value we add to the university on a daily basis is clearly visible. Many personnel members contributed to make the UFS a valued institution and will proceed to do that in the spirit of 100+.”

He thanked and acknowledged personnel for the plus they add to each day’s work. “The students which enter the UFS each year, want to thank you for an university which on an innovative manner impacted their lives. “You helped to create the building blocks for their future,” he said.

Prof. J. F. Botha, Mr M.G. Botha, Ms A. De Klerk, Mr M.J. Doman, Prof. H.C. Janse van Rensburg and Ms S.M.C. Reinecke received awards for 35 years of service.

For 25 years of service at the university Prof. S.L. Barnard, Mr B. Botma, Dr H. J. Breytenbach, Dr M.W. Brussow, Mr N.L. Combrink, Ms A.J. Du Plessis, Ms C. Du Plessis, Prof. L. Goedhals, Mr M.E. Hlazo, Prof. B.B. Hoek, Dr S.J.E. Janse van Vuuren, Mr M. Kgasane, Ms A. Kgosi, Dr W.P. Konig, Dr P.A.L. Le Roux, Prof. N.J. Luwes, Dr N. Luyt, Ms S.E. November, Ms M. Mabaso, Ms M.K. Maruping, Prof. J.D. Marx, Mr J.P. Masedi, Mr G. Mokapane, Mr J. Mokapane, Ms M.L. Molosi, Ms M.M. Molwagale, Mr P.J. Moorosi, Ms C. Moroagae, Ms E. Moroale, Mr G.G. Mothokwane, Prof. M. Mulder, Prof. A.C. Otto, Ms H. Pelser, Ms E. Pelzer, Ms M.M. Pheko, Prof. E. Pretorius, Ms M.P. Richter, Ms E. Rouls, Prof. M.T. Seaman, Prof. R.B. Snowdowne, Prof. J.P. Strauss, Ms M.S. Tsolo, Prof. H.J. van der Linde, Dr S. van Vuuren, Prof. J.B. van Wyk, Dr J.M. van Zyl, Prof. T. Verschoor and Ms M.H.S. York received an long service award.

“Be assured of my appreciation for your loyalty and commitment to a university which is taking careful steps into a new century of its existence. If we do the right things right and with a sincere belief in our heavenly Father we will be able to build on the solid foundation laid by people like you,” he said.

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