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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Protest actions on the Main Campus
2008-03-12

Staff and students are kindly requested to take note of the following protest actions that will take place on the Main Campus.

As a result of a dispute over the status of roads on campus, permission was granted by the municipality and the court, in the presence of the university lawyer for the three actions. Strict conditions have been set for these protest actions.

a.) On Wednesday, 12 March 2008, Satawu and Nehawu will picket in front of the Main Building from 09:00 to 12:00. Three hundred persons will possibly attend this event. Marchers are not allowed within 10 meters from the Main Building and there will be 45 marshals present. This is not a march and no memorandum will be handed over. There may be no speeches.

b.) On Thursday, 13 March Nehawu will again picket in front of the Main Building from 13:00 to 14:00. This event must be peaceful. Only 125 Nehawu members may participate and protesters may not break away from the big group. They may not come within 10 meters of the Main Building. Twenty five of the protesters will be marshals. This is not a march and no memorandum will be handed over. No speeches may be made.

c.) On Friday, 14 March a march of Cosatu and Nehawu will take place. This march will probably be joined by a big number of people.

The march will continue through the Nelson Mandela Gate and will enter the campus grounds, but will be limited to the incoming lane of Chancellors Avenue from the Main Gate to the crossing with Alumni Avenue (in front of the Odeion). Speeches will be made and a memorandum will be handed over.

The march will reach the campus at 10:00 and from then the Nelson Mandela Gate will be closed for all traffic. The march must be finished by 14:00. The marchers will return to the city centre and could cause a traffic problem in Nelson Mandela Avenue.

The South African Police Service and the UFS’s Protection Service will monitor all these actions. Staff are kindly requested to use alternative gates to the Nelson Mandela entrance on Friday. Academic activities continue as normal.

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