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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Protest actions planned for 12-14 March 2008
2008-03-13

Three protest actions will take place on the Main Campus of the University of the Free State (UFS) in Bloemfontein this week.

Although the interim court interdict granted to the UFS on 6 March 2008 is still in force, permission for the three protests was granted by the Mangaung Local Municipality and the court, in the presence of the university lawyer. Strict conditions have been set for these protest actions.

The UFS management respects the right to peaceful protest and also shares the sentiment of the protesters regarding the reprehensible Reitz video. However, strict conditions have been set for these protest actions as students are writing tests and the normal academic activities should not be disrupted.

Already the first picket protest took place today, Wednesday, 12 March 2008, by about 300 Satawu and Nehawu members. This was not a march and no memorandum was handed over.

On Thursday, 13 March 2008, Nehawu will again picket in front of the Main Building from 13:00 to 14:00. This event must be peaceful. This too is not a march and no memorandum will be handed over.

On Friday, 14 March 2008, a march of Cosatu and Nehawu will take place, starting in the city centre. The march will enter through the Nelson Mandela Drive gate and will enter the campus grounds.

However, it will be limited to the incoming lane of Chancellors Avenue from the Main Gate to the crossing with Alumni Avenue (in front of the Odeion building). Speeches will be made and a memorandum will be handed over.

It is expected that the march will reach the campus at approximately 10:00 and from then the Nelson Mandela Gate to the UFS will be closed for all traffic. The march must end by 14:00. The marchers will return to the city centre and may cause a traffic problem in Nelson Mandela Drive.

The South African Police Service (SAPS) and the UFS’s Protection Services Division will monitor all these actions. Staff, students and visitors to the campus are kindly requested to use alternative gates to the Nelson Mandela entrance on Friday. Academic activities will continue as normal this week.

Media Release
Issued by: Anton Fisher
Director: Strategic Communication
Tel: 051 401 3422
Cell: 072 207 8334
E-mail: fishera.stg@ufs.ac.za  
12 March 2008


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