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19 July 2018 Photo Supplied
AEVGI advances Next-Generation Sequencing in Africa
Prof George Armah, Noguchi Memorial Institute for Medical Research, Ghana; Prof Carl Kirkwood, Bill and Melinda Gates Foundation, USA; Cornelius Hagenmeier, Director: Internationalisation, UFS; Prof Gert van Zyl, Dean: Health Sciences; Dr Martin Nyaga, Senior Lecturer in the NGS Unit; Prof Joyce Tsoka-Gwegweni, Vice-Dean: Health Sciences; Dr Glen Taylor, Senior Director: Research and Development; Prof Jeffrey Mphahlele, Vice-President, South African Medical Research Council.

The inaugural edition of the University of the Free State (UFS) Next-Generation Sequencing (NGS) Data and Bioinformatics Workshop, hosted by the UFS-NGS Unit in the UFS Faculty of Health Sciences, marked a new beginning for the advancement of NGS in Africa under the auspices of the African Enteric Viruses Genome Initiative (AEVGI), which was recently funded by the Bill and Melinda Gates Foundation.

The AEVGI will generate rotavirus genomes at the UFS-NGS Unit to investigate the long-term effects of the introduction of the monovalent RV1 vaccine in three African countries – Ghana, Malawi, and South Africa.

The workshop attracted over 90 participants from 15 national and international institutions, with organisations from seven different countries as well as company representatives attending the event. The workshop kicked off with a courtesy call to the Rector and Vice-Chancellor, Prof Francis Petersen, followed by a stakeholder meeting with the executive management of the UFS.

The funding was secured through an award to the principal investigator, Dr Martin Nyaga, and sub-awards to co-investigators, Dr Khuzwayo Jere, Dr Francis Dennis, and Dr Valentine Ndze. According to attendee evaluations of the workshop, the remarkable performance of the workshop instructors was outstanding. Through practical sessions, participants were equipped with knowledge on how to apply several tools of genetic data analysis, using the rotavirus genome as a model to construct and interpret different genomic datasets.

A total of 65 students attended the hands-on workshop, the majority of which were from South African higher-education institutions. The organisers are grateful to the sponsors, particularly to the Bill and Melinda Gates Foundation and the University of the Free State, for making the workshop a success. Whitehead Scientific and the South African Medical Research Council also played a major role in the success of the workshop. The local organising committee consisted of Dr Martin Nyaga (host, convener and chair), Dr Saheed Sabiu (secretary), and Mr Stephanus Riekert (principal ICT support).

News Archive

Blood tests for players at FIFA Confederations Cup
2009-03-21

Football stars coming to South Africa to play in the FIFA Confederations Cup tournament in June will not only have their urine tested for illegal substances but their blood as well.

This will be the first time that blood samples from sportsmen or women will be tested in South Africa.

“Blood testing is a new regulation from the World Anti-Doping Agency (WADA) and will be implemented in our laboratory for the FIFA Confederations Cup in June,” according to Dr Pieter van der Merwe, Head of the SA Doping Control Laboratory at the University of the Free State (UFS), the only testing facility of its kind in Southern Africa.

Although urine will still be tested, blood tests have become compulsory, because the substances used by sports men and women are becoming more sophisticated.

“Some substances, such as the growth hormone, can more easily be detected in blood. It is more difficult to determine these kinds of substances in urine,” explained Dr Van der Merwe.

“We were contracted by the International Rugby Board (IRB) to conduct the testing for the 7’s World Cup Rugby Tournament that was recently held in Dubai and by FIFA to do the testing for the Confederations Cup this year as well as the 2010 World Cup. This demonstrates the confidence of International Sport Federations in the quality and standard of work produced by this facility at the UFS,” he said.

The results of all tests done for the national programme in South Africa are sent to the Institute for Drug Free Sport based in Cape Town from where it is reported to the various sports federations. However, the rugby and soccer results are reported directly to the IRB and FIFA respectively.

The move to incorporate blood tests in the testing process has resulted in the expansion of the facility’s infrastructure.

“A new extension will be built for us in the near future in order for us to accommodate the conducting of urine and blood testing,” says Dr van der Merwe.

Media Release
Issued by: Anton Fisher
Director: Strategic Communication
Tel: 051 401 2749
Cell: 072 207 8334
E-mail: fishera.stg@ufs.ac.za  
20 March 2009

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