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19 July 2018 Photo Supplied
AEVGI advances Next-Generation Sequencing in Africa
Prof George Armah, Noguchi Memorial Institute for Medical Research, Ghana; Prof Carl Kirkwood, Bill and Melinda Gates Foundation, USA; Cornelius Hagenmeier, Director: Internationalisation, UFS; Prof Gert van Zyl, Dean: Health Sciences; Dr Martin Nyaga, Senior Lecturer in the NGS Unit; Prof Joyce Tsoka-Gwegweni, Vice-Dean: Health Sciences; Dr Glen Taylor, Senior Director: Research and Development; Prof Jeffrey Mphahlele, Vice-President, South African Medical Research Council.

The inaugural edition of the University of the Free State (UFS) Next-Generation Sequencing (NGS) Data and Bioinformatics Workshop, hosted by the UFS-NGS Unit in the UFS Faculty of Health Sciences, marked a new beginning for the advancement of NGS in Africa under the auspices of the African Enteric Viruses Genome Initiative (AEVGI), which was recently funded by the Bill and Melinda Gates Foundation.

The AEVGI will generate rotavirus genomes at the UFS-NGS Unit to investigate the long-term effects of the introduction of the monovalent RV1 vaccine in three African countries – Ghana, Malawi, and South Africa.

The workshop attracted over 90 participants from 15 national and international institutions, with organisations from seven different countries as well as company representatives attending the event. The workshop kicked off with a courtesy call to the Rector and Vice-Chancellor, Prof Francis Petersen, followed by a stakeholder meeting with the executive management of the UFS.

The funding was secured through an award to the principal investigator, Dr Martin Nyaga, and sub-awards to co-investigators, Dr Khuzwayo Jere, Dr Francis Dennis, and Dr Valentine Ndze. According to attendee evaluations of the workshop, the remarkable performance of the workshop instructors was outstanding. Through practical sessions, participants were equipped with knowledge on how to apply several tools of genetic data analysis, using the rotavirus genome as a model to construct and interpret different genomic datasets.

A total of 65 students attended the hands-on workshop, the majority of which were from South African higher-education institutions. The organisers are grateful to the sponsors, particularly to the Bill and Melinda Gates Foundation and the University of the Free State, for making the workshop a success. Whitehead Scientific and the South African Medical Research Council also played a major role in the success of the workshop. The local organising committee consisted of Dr Martin Nyaga (host, convener and chair), Dr Saheed Sabiu (secretary), and Mr Stephanus Riekert (principal ICT support).

News Archive

UFS leads the way with GMO testing
2003-08-25

A formal agreement linking Africa’s first testing facility for genetically modified organisms (GMO) to an international organization was signed at the University of the Free State.

According to the manager of the GMO testing facility, Dr Chris Viljoen of the Department of Plant Sciences, the facility is now part of GeneScan, a world leader in food diagnostic testing, which has its headquarters in Germany with subsidiaries in the Unites States, Brazil and Hong Kong.

The facility at the UFS has been selected by the second largest international food company to do all its South African GMO testing for export products.

The GMO testing facility is the brainchild of Dr Viljoen, who is a specialist in the field of marker biotechnology and its applications in crop science.

He says the need for such a testing facility arose due to the international regulations on GMOs in food, especially Europe and Asia that requires South African exporters to certify whether their products contain any GMO.

“The regulations in Europe and Asia reflect a consumer need for choice in what they eat due to concerns over the safety of GMOs, as well as environmental and ethical issues. GMO testing and labelling allow consumers the right of choice to eat genetically modified foods or not. According to EU regulations, any product with a GMO content of 1% or higher is labelled as containing GMO.”

According to Dr Viljoen only four products in South Africa are currently GMO. They are white and yellow maize that have been made insect resistant, soya bean that is herbicide tolerant and insect resistant cotton. He says that the awareness of GMOs among South Africans is still very limited, especially in poorer communities, but it is likely to increase with the efforts being made in consumer education by government, seed companies and NGOs.

The testing facility has been established to accommodate the local as well as international market. The GMO testing at the UFS facility is performed using real time PCR, the most advanced means of GMO detection currently available, and using GeneScan developed technology that is recognized worldwide.
 

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