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AEVGI advances Next-Generation Sequencing in Africa
Prof George Armah, Noguchi Memorial Institute for Medical Research, Ghana; Prof Carl Kirkwood, Bill and Melinda Gates Foundation, USA; Cornelius Hagenmeier, Director: Internationalisation, UFS; Prof Gert van Zyl, Dean: Health Sciences; Dr Martin Nyaga, Senior Lecturer in the NGS Unit; Prof Joyce Tsoka-Gwegweni, Vice-Dean: Health Sciences; Dr Glen Taylor, Senior Director: Research and Development; Prof Jeffrey Mphahlele, Vice-President, South African Medical Research Council.

The inaugural edition of the University of the Free State (UFS) Next-Generation Sequencing (NGS) Data and Bioinformatics Workshop, hosted by the UFS-NGS Unit in the UFS Faculty of Health Sciences, marked a new beginning for the advancement of NGS in Africa under the auspices of the African Enteric Viruses Genome Initiative (AEVGI), which was recently funded by the Bill and Melinda Gates Foundation.

The AEVGI will generate rotavirus genomes at the UFS-NGS Unit to investigate the long-term effects of the introduction of the monovalent RV1 vaccine in three African countries – Ghana, Malawi, and South Africa.

The workshop attracted over 90 participants from 15 national and international institutions, with organisations from seven different countries as well as company representatives attending the event. The workshop kicked off with a courtesy call to the Rector and Vice-Chancellor, Prof Francis Petersen, followed by a stakeholder meeting with the executive management of the UFS.

The funding was secured through an award to the principal investigator, Dr Martin Nyaga, and sub-awards to co-investigators, Dr Khuzwayo Jere, Dr Francis Dennis, and Dr Valentine Ndze. According to attendee evaluations of the workshop, the remarkable performance of the workshop instructors was outstanding. Through practical sessions, participants were equipped with knowledge on how to apply several tools of genetic data analysis, using the rotavirus genome as a model to construct and interpret different genomic datasets.

A total of 65 students attended the hands-on workshop, the majority of which were from South African higher-education institutions. The organisers are grateful to the sponsors, particularly to the Bill and Melinda Gates Foundation and the University of the Free State, for making the workshop a success. Whitehead Scientific and the South African Medical Research Council also played a major role in the success of the workshop. The local organising committee consisted of Dr Martin Nyaga (host, convener and chair), Dr Saheed Sabiu (secretary), and Mr Stephanus Riekert (principal ICT support).

News Archive

School dropouts are more vulnerable to HIV
2010-02-02

 Prof. Dennis Francis

Children who drop out of school miss out on information about HIV/Aids and reproduction health, according to research conducted by Prof. Dennis Francis, Dean of the Faculty of Education at the University of the Free State.

The research entitled “Towards understanding the way out-of-school youth respond to HIV/Aids” included out-of-school youths as researchers and identified key issues and problems facing them. It covered youths between the ages of 14 to 18.

The study, funded by the Medical Research Council of South Africa, showed that schools played a vital role in providing credible information on HIV/Aids and ways to prevent it.

It also found that these out-of-school youths believed that HIV/Aids was a non-issue and deliberately avoided the subject, with boys being the main culprits.

The researchers found that these youths got their information on HIV/Aids from friends, community healthcare workers, religious leaders, family and other youngsters. The way they responded to HIV/Aids varied and often depended on their social context, effects on their self esteem and sense of power, according to Prof. Francis.

They also discovered that knowledge about HIV/Aids did not necessarily translate into action.

“School-going youth displayed similar difficulties in applying knowledge in real-life situations and lacked the tools for doing so,” he said. “But, unlike school-going youth, out-of-school youth did not have the option of using the school environment to speak about misconceptions.”

These finding will be presented at the United Nations Education, Scientific and Cultural Organisation-funded Hope 2010 Conference in India.

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za  
2 February 2010

 

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