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19 July 2018 Photo Supplied
AEVGI advances Next-Generation Sequencing in Africa
Prof George Armah, Noguchi Memorial Institute for Medical Research, Ghana; Prof Carl Kirkwood, Bill and Melinda Gates Foundation, USA; Cornelius Hagenmeier, Director: Internationalisation, UFS; Prof Gert van Zyl, Dean: Health Sciences; Dr Martin Nyaga, Senior Lecturer in the NGS Unit; Prof Joyce Tsoka-Gwegweni, Vice-Dean: Health Sciences; Dr Glen Taylor, Senior Director: Research and Development; Prof Jeffrey Mphahlele, Vice-President, South African Medical Research Council.

The inaugural edition of the University of the Free State (UFS) Next-Generation Sequencing (NGS) Data and Bioinformatics Workshop, hosted by the UFS-NGS Unit in the UFS Faculty of Health Sciences, marked a new beginning for the advancement of NGS in Africa under the auspices of the African Enteric Viruses Genome Initiative (AEVGI), which was recently funded by the Bill and Melinda Gates Foundation.

The AEVGI will generate rotavirus genomes at the UFS-NGS Unit to investigate the long-term effects of the introduction of the monovalent RV1 vaccine in three African countries – Ghana, Malawi, and South Africa.

The workshop attracted over 90 participants from 15 national and international institutions, with organisations from seven different countries as well as company representatives attending the event. The workshop kicked off with a courtesy call to the Rector and Vice-Chancellor, Prof Francis Petersen, followed by a stakeholder meeting with the executive management of the UFS.

The funding was secured through an award to the principal investigator, Dr Martin Nyaga, and sub-awards to co-investigators, Dr Khuzwayo Jere, Dr Francis Dennis, and Dr Valentine Ndze. According to attendee evaluations of the workshop, the remarkable performance of the workshop instructors was outstanding. Through practical sessions, participants were equipped with knowledge on how to apply several tools of genetic data analysis, using the rotavirus genome as a model to construct and interpret different genomic datasets.

A total of 65 students attended the hands-on workshop, the majority of which were from South African higher-education institutions. The organisers are grateful to the sponsors, particularly to the Bill and Melinda Gates Foundation and the University of the Free State, for making the workshop a success. Whitehead Scientific and the South African Medical Research Council also played a major role in the success of the workshop. The local organising committee consisted of Dr Martin Nyaga (host, convener and chair), Dr Saheed Sabiu (secretary), and Mr Stephanus Riekert (principal ICT support).

News Archive

Dr Chantel Swart the ‘Expert on Stage’
2013-06-04

 

Presents Extraordinary Findings at International Nanomedicine Conference.
Photo: Sonia Small
04 June 2013

Dr Chantel Swart, an alumnus of the Prestige Scholars Programme (PSP) from the Department of Microbial, Biochemical and Food Biotechnology, is an invited “Expert on Stage” at the 4th International Nanomedicine Conference to be held in Sydney, Australia from 1 – 3 July 2013.

She is to share the podium with world authorities in nanomedicine.

Dr Swart’s presentation, “A New Nanotechnology for Nanomedicine”, will convey findings that made international headlines. She is part of the nanotechnology group of Prof Lodewyk Kock that discovered gas bubbles inside cells when using Auger-architectomics, a nanotechnology they developed in 2010. This nanotechnology is used to track nanomedicine inside cancer cells in collaboration with the Mayo Clinic in the US.

The Kock Nanotechnology Group includes scholars from the departments of Microbial, Biochemical and Food Biotechnology, Physics, Chemistry, the Centre for Microscopy (all from the UFS) and South African Breweries. Their breakthrough is also showcased on the cover of all issues of 2013 FEMS Yeast Research, a leading journal in yeast research. BiotecVisions and Global Medical Discovery (GMD) both selected this work for worldwide promotion at the end of 2012.

Dr Swart’s future research will use this newly-developed nanotechnology to visualize and hence explore the exposed nano-world. This will include work on the architecture of cells and effects of various drugs on cell metabolism.

A virtual tour is available at: http://vimeo.com/user6296337/videos.

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