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19 July 2018 Photo Supplied
AEVGI advances Next-Generation Sequencing in Africa
Prof George Armah, Noguchi Memorial Institute for Medical Research, Ghana; Prof Carl Kirkwood, Bill and Melinda Gates Foundation, USA; Cornelius Hagenmeier, Director: Internationalisation, UFS; Prof Gert van Zyl, Dean: Health Sciences; Dr Martin Nyaga, Senior Lecturer in the NGS Unit; Prof Joyce Tsoka-Gwegweni, Vice-Dean: Health Sciences; Dr Glen Taylor, Senior Director: Research and Development; Prof Jeffrey Mphahlele, Vice-President, South African Medical Research Council.

The inaugural edition of the University of the Free State (UFS) Next-Generation Sequencing (NGS) Data and Bioinformatics Workshop, hosted by the UFS-NGS Unit in the UFS Faculty of Health Sciences, marked a new beginning for the advancement of NGS in Africa under the auspices of the African Enteric Viruses Genome Initiative (AEVGI), which was recently funded by the Bill and Melinda Gates Foundation.

The AEVGI will generate rotavirus genomes at the UFS-NGS Unit to investigate the long-term effects of the introduction of the monovalent RV1 vaccine in three African countries – Ghana, Malawi, and South Africa.

The workshop attracted over 90 participants from 15 national and international institutions, with organisations from seven different countries as well as company representatives attending the event. The workshop kicked off with a courtesy call to the Rector and Vice-Chancellor, Prof Francis Petersen, followed by a stakeholder meeting with the executive management of the UFS.

The funding was secured through an award to the principal investigator, Dr Martin Nyaga, and sub-awards to co-investigators, Dr Khuzwayo Jere, Dr Francis Dennis, and Dr Valentine Ndze. According to attendee evaluations of the workshop, the remarkable performance of the workshop instructors was outstanding. Through practical sessions, participants were equipped with knowledge on how to apply several tools of genetic data analysis, using the rotavirus genome as a model to construct and interpret different genomic datasets.

A total of 65 students attended the hands-on workshop, the majority of which were from South African higher-education institutions. The organisers are grateful to the sponsors, particularly to the Bill and Melinda Gates Foundation and the University of the Free State, for making the workshop a success. Whitehead Scientific and the South African Medical Research Council also played a major role in the success of the workshop. The local organising committee consisted of Dr Martin Nyaga (host, convener and chair), Dr Saheed Sabiu (secretary), and Mr Stephanus Riekert (principal ICT support).

News Archive

Meet Dr Aliza le Roux, Prestige Scholar
2013-07-10

 

Dr Aliza le Roux
Ground-breaking research on gelada ape made waves.
Photo: Sonia Small
10 July 2013


Dr Aliza le Roux is an NRF Y2-rated senior lecturer in the Department of Zoology and Entomology on the Qwaqwa Campus. She joined the Vice-Chancellor’s Prestige Scholars Programme (PSP) in 2013.

Dr le Roux has devoted the past decade to research on the cognitive and communicative skills of wild mammals in the arid regions of South Africa and the highlands of Ethiopia.

She spent four years as postdoctoral research fellow at the University of Michigan, leading to ground-breaking work on the cognitive and communicative underpinnings of gelada monkey behaviour. This was published in Nature Communications and created waves in the international scholarly community.

Most recently, Dr le Roux has focused on the paternal care of an eccentric canid– the bat-eared fox. She is convinced that we have much to learn about ourselves from animals outside the primate order. This unusual little fox eats mainly termites, and males – rather than females – take care of the offspring. The reason why, is still a mystery Dr le Roux hopes to unravel. Little is known about the physiological stress that foxes face, or how paternal care affects the father, the mother, and the pups. Even in humans, the true impact of paternal care is poorly understood.

With this ground-breaking project, Dr le Roux hopes not only to describe the ecology and physiology of fatherhood, but also how a father’s care can affect the cognitive development of his offspring.

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