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19 July 2018 Photo Supplied
AEVGI advances Next-Generation Sequencing in Africa
Prof George Armah, Noguchi Memorial Institute for Medical Research, Ghana; Prof Carl Kirkwood, Bill and Melinda Gates Foundation, USA; Cornelius Hagenmeier, Director: Internationalisation, UFS; Prof Gert van Zyl, Dean: Health Sciences; Dr Martin Nyaga, Senior Lecturer in the NGS Unit; Prof Joyce Tsoka-Gwegweni, Vice-Dean: Health Sciences; Dr Glen Taylor, Senior Director: Research and Development; Prof Jeffrey Mphahlele, Vice-President, South African Medical Research Council.

The inaugural edition of the University of the Free State (UFS) Next-Generation Sequencing (NGS) Data and Bioinformatics Workshop, hosted by the UFS-NGS Unit in the UFS Faculty of Health Sciences, marked a new beginning for the advancement of NGS in Africa under the auspices of the African Enteric Viruses Genome Initiative (AEVGI), which was recently funded by the Bill and Melinda Gates Foundation.

The AEVGI will generate rotavirus genomes at the UFS-NGS Unit to investigate the long-term effects of the introduction of the monovalent RV1 vaccine in three African countries – Ghana, Malawi, and South Africa.

The workshop attracted over 90 participants from 15 national and international institutions, with organisations from seven different countries as well as company representatives attending the event. The workshop kicked off with a courtesy call to the Rector and Vice-Chancellor, Prof Francis Petersen, followed by a stakeholder meeting with the executive management of the UFS.

The funding was secured through an award to the principal investigator, Dr Martin Nyaga, and sub-awards to co-investigators, Dr Khuzwayo Jere, Dr Francis Dennis, and Dr Valentine Ndze. According to attendee evaluations of the workshop, the remarkable performance of the workshop instructors was outstanding. Through practical sessions, participants were equipped with knowledge on how to apply several tools of genetic data analysis, using the rotavirus genome as a model to construct and interpret different genomic datasets.

A total of 65 students attended the hands-on workshop, the majority of which were from South African higher-education institutions. The organisers are grateful to the sponsors, particularly to the Bill and Melinda Gates Foundation and the University of the Free State, for making the workshop a success. Whitehead Scientific and the South African Medical Research Council also played a major role in the success of the workshop. The local organising committee consisted of Dr Martin Nyaga (host, convener and chair), Dr Saheed Sabiu (secretary), and Mr Stephanus Riekert (principal ICT support).

News Archive

Shimlas get back on track
2014-02-26

The Shimlas overpowered a startled UJ side in Bloemfontein on Monday, scoring seven tries en route to a 52-16 victory in the fourth round of the Varsity Cup competition.

The UFS’s second win in four weeks saw them climb the log standings to a well deserved third position. The Shimlas took an early lead in the match, with blindside flank Oupa Mohoje scoring the opening try from an attacking line-out.

Our boytjies was on a roll, with wing Maphuto Dolo scoring in the corner after a break from a scrum by scrumhalf Kevin Luiters. Kovsies' flyhalf Gouws Prinsloo knocked both conversions over to put our team in a commanding 16-0 lead before the first strategy break. Not long after, the Shimlas scored their third try as left wing Sethu Tom found the corner to make it 21-0. T his was followed by yet another onslaught when Shimlas’ skipper, Joubert Engelbrecht, crashed over for the bonus-point try. Outside centre, Tertius Kruger, put even more pressure on the UJ side when he crossed the try line, leaving the Shimlas with a 34-0 lead at half-time.

Prinsloo slotted a penalty early in the second half for Shimlas, followed by skipper Engelbrecht’s second try. After 15 minutes into the second half, UJ managed to score two converted tries to change the scoreboard to 44-16. T his did, however, not spur the visitors on to complete a comeback and the Shimlas' Divandré Strydom gave our team the last say with one final try.

The scorers:
For FNB UFS-Shimlas:
Tries: Oupa Mohoje, Maphuto Dolo, Sethu Tom, Joubert Engelbrecht (2), Tertius Kruger, Divandré Strydom
Cons: Gouws Prinsloo (5)
Pen: Gouws Prinsloo

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