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AEVGI advances Next-Generation Sequencing in Africa
Prof George Armah, Noguchi Memorial Institute for Medical Research, Ghana; Prof Carl Kirkwood, Bill and Melinda Gates Foundation, USA; Cornelius Hagenmeier, Director: Internationalisation, UFS; Prof Gert van Zyl, Dean: Health Sciences; Dr Martin Nyaga, Senior Lecturer in the NGS Unit; Prof Joyce Tsoka-Gwegweni, Vice-Dean: Health Sciences; Dr Glen Taylor, Senior Director: Research and Development; Prof Jeffrey Mphahlele, Vice-President, South African Medical Research Council.

The inaugural edition of the University of the Free State (UFS) Next-Generation Sequencing (NGS) Data and Bioinformatics Workshop, hosted by the UFS-NGS Unit in the UFS Faculty of Health Sciences, marked a new beginning for the advancement of NGS in Africa under the auspices of the African Enteric Viruses Genome Initiative (AEVGI), which was recently funded by the Bill and Melinda Gates Foundation.

The AEVGI will generate rotavirus genomes at the UFS-NGS Unit to investigate the long-term effects of the introduction of the monovalent RV1 vaccine in three African countries – Ghana, Malawi, and South Africa.

The workshop attracted over 90 participants from 15 national and international institutions, with organisations from seven different countries as well as company representatives attending the event. The workshop kicked off with a courtesy call to the Rector and Vice-Chancellor, Prof Francis Petersen, followed by a stakeholder meeting with the executive management of the UFS.

The funding was secured through an award to the principal investigator, Dr Martin Nyaga, and sub-awards to co-investigators, Dr Khuzwayo Jere, Dr Francis Dennis, and Dr Valentine Ndze. According to attendee evaluations of the workshop, the remarkable performance of the workshop instructors was outstanding. Through practical sessions, participants were equipped with knowledge on how to apply several tools of genetic data analysis, using the rotavirus genome as a model to construct and interpret different genomic datasets.

A total of 65 students attended the hands-on workshop, the majority of which were from South African higher-education institutions. The organisers are grateful to the sponsors, particularly to the Bill and Melinda Gates Foundation and the University of the Free State, for making the workshop a success. Whitehead Scientific and the South African Medical Research Council also played a major role in the success of the workshop. The local organising committee consisted of Dr Martin Nyaga (host, convener and chair), Dr Saheed Sabiu (secretary), and Mr Stephanus Riekert (principal ICT support).

News Archive

The mysterious origins and problematic significance of the Postamble
2014-10-20



Prof André du Toit (UCT) and Prof Pieter Duvenhage (UFS)
Emeritus professor from UCT’s Department of Political Studies, Prof André du Toit, delivered a presentation at the Bloemfontein Campus on 14, 15 and 16 October 2014 respectively. His presentations gave an in-depth exploration of the Postamble as founding text of the South African Truth and Reconciliation Commission (TRC).

This event was hosted by the Institute for Reconciliation and Social Justice, in collaboration with the Department of Philosophy.

Prof Du Toit’s papers were entitled:
•    A Need for Truth: Amnesty and the Origins and Consequences of the TRC Process.
•    Tracking down a belated and inconclusive amnesty pact: The obscure origins and problematic significance of the 'Postamble' as founding text of the TRC process (Part 1 and 2).

In his presentations he explored how the text of the Postamble came to be written. He also scrutinised the respective contributions of those who were involved in drafting the text. The significance of the Postamble – as it is understood in its historical context – was also a point of discussion.

Prof Du Toit raised some thought-provoking questions during the three days. What is the relation of the amnesty provision of the Postamble with the subsequent TRC amnesty process? How did a text without any particular reference to a truth commission come to function as founding text and discursive framework for the TRC?

He also investigated some of the main problems with the history and significance of the Postamble, as well as its mysterious origins. In addition, Prof Du Toit conducted a critical analysis of a set of newly-identified drafts of the text.

One of Prof Du Toit’s most substantive inquiries, though, was into the question: Was the amnesty provision of the Postamble the product of an underlying amnesty ‘pact’ between the NP government and the ANC?


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