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19 July 2018 Photo Supplied
AEVGI advances Next-Generation Sequencing in Africa
Prof George Armah, Noguchi Memorial Institute for Medical Research, Ghana; Prof Carl Kirkwood, Bill and Melinda Gates Foundation, USA; Cornelius Hagenmeier, Director: Internationalisation, UFS; Prof Gert van Zyl, Dean: Health Sciences; Dr Martin Nyaga, Senior Lecturer in the NGS Unit; Prof Joyce Tsoka-Gwegweni, Vice-Dean: Health Sciences; Dr Glen Taylor, Senior Director: Research and Development; Prof Jeffrey Mphahlele, Vice-President, South African Medical Research Council.

The inaugural edition of the University of the Free State (UFS) Next-Generation Sequencing (NGS) Data and Bioinformatics Workshop, hosted by the UFS-NGS Unit in the UFS Faculty of Health Sciences, marked a new beginning for the advancement of NGS in Africa under the auspices of the African Enteric Viruses Genome Initiative (AEVGI), which was recently funded by the Bill and Melinda Gates Foundation.

The AEVGI will generate rotavirus genomes at the UFS-NGS Unit to investigate the long-term effects of the introduction of the monovalent RV1 vaccine in three African countries – Ghana, Malawi, and South Africa.

The workshop attracted over 90 participants from 15 national and international institutions, with organisations from seven different countries as well as company representatives attending the event. The workshop kicked off with a courtesy call to the Rector and Vice-Chancellor, Prof Francis Petersen, followed by a stakeholder meeting with the executive management of the UFS.

The funding was secured through an award to the principal investigator, Dr Martin Nyaga, and sub-awards to co-investigators, Dr Khuzwayo Jere, Dr Francis Dennis, and Dr Valentine Ndze. According to attendee evaluations of the workshop, the remarkable performance of the workshop instructors was outstanding. Through practical sessions, participants were equipped with knowledge on how to apply several tools of genetic data analysis, using the rotavirus genome as a model to construct and interpret different genomic datasets.

A total of 65 students attended the hands-on workshop, the majority of which were from South African higher-education institutions. The organisers are grateful to the sponsors, particularly to the Bill and Melinda Gates Foundation and the University of the Free State, for making the workshop a success. Whitehead Scientific and the South African Medical Research Council also played a major role in the success of the workshop. The local organising committee consisted of Dr Martin Nyaga (host, convener and chair), Dr Saheed Sabiu (secretary), and Mr Stephanus Riekert (principal ICT support).

News Archive

Traditional medicine can play important role in modern drugs discovery
2014-11-11

Indigenous knowledge possesses a great potential to improve science. Making use of this source may lead to advanced technological innovations. This is according to Dr Sechaba Bareetseng, UFS alumnus and Indigenous Knowledge Systems (IKS) Manager at the Council for Scientific and Industrial Research (CSIR).
Dr Bareetseng recently addressed the seventh annual IKS symposium on the Qwaqwa Campus.
“Interfacing indigenous and local knowledge with scientific knowledge has the potential of encouraging and developing inventions, especially in the pharmaceutical industry,” said Dr Bareetseng.
 
“Such interfacing can also enable access to both sets of knowledge without any discrimination whatsoever. It would also encourage co-existence that would improve understanding between the two.”
 
“Traditional medicine,” said Dr Bareetseng, “can play an extended role in modern drugs discovery as it is already happening in Botswana and New Zealand. These two countries are leading this wave of new thinking in as far as drug development is concerned.”
 
Dr Bareetseng also called on established researchers to start embracing the local communities into their research.
 
“Contemporary scientific research demands that local communities must co-author research conducted within and with them by the universities and research institutions. This would help in maintaining trust between the researchers and the communities that feel exploited. Regular feedback would also make communities feel part of the developments,” Dr Bareetseng argued.
 
He further called on the pharmaceutical companies specifically and researchers in general to convert valuable indigenous knowledge and resources into products and services of commercial value. “Plants, the ecosystem and indigenous knowledge must be preserved to provide a source of income for the local communities. Communities must also be protected from foreign exploitation of their intellectual property.”
 

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