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19 July 2018 Photo Supplied
AEVGI advances Next-Generation Sequencing in Africa
Prof George Armah, Noguchi Memorial Institute for Medical Research, Ghana; Prof Carl Kirkwood, Bill and Melinda Gates Foundation, USA; Cornelius Hagenmeier, Director: Internationalisation, UFS; Prof Gert van Zyl, Dean: Health Sciences; Dr Martin Nyaga, Senior Lecturer in the NGS Unit; Prof Joyce Tsoka-Gwegweni, Vice-Dean: Health Sciences; Dr Glen Taylor, Senior Director: Research and Development; Prof Jeffrey Mphahlele, Vice-President, South African Medical Research Council.

The inaugural edition of the University of the Free State (UFS) Next-Generation Sequencing (NGS) Data and Bioinformatics Workshop, hosted by the UFS-NGS Unit in the UFS Faculty of Health Sciences, marked a new beginning for the advancement of NGS in Africa under the auspices of the African Enteric Viruses Genome Initiative (AEVGI), which was recently funded by the Bill and Melinda Gates Foundation.

The AEVGI will generate rotavirus genomes at the UFS-NGS Unit to investigate the long-term effects of the introduction of the monovalent RV1 vaccine in three African countries – Ghana, Malawi, and South Africa.

The workshop attracted over 90 participants from 15 national and international institutions, with organisations from seven different countries as well as company representatives attending the event. The workshop kicked off with a courtesy call to the Rector and Vice-Chancellor, Prof Francis Petersen, followed by a stakeholder meeting with the executive management of the UFS.

The funding was secured through an award to the principal investigator, Dr Martin Nyaga, and sub-awards to co-investigators, Dr Khuzwayo Jere, Dr Francis Dennis, and Dr Valentine Ndze. According to attendee evaluations of the workshop, the remarkable performance of the workshop instructors was outstanding. Through practical sessions, participants were equipped with knowledge on how to apply several tools of genetic data analysis, using the rotavirus genome as a model to construct and interpret different genomic datasets.

A total of 65 students attended the hands-on workshop, the majority of which were from South African higher-education institutions. The organisers are grateful to the sponsors, particularly to the Bill and Melinda Gates Foundation and the University of the Free State, for making the workshop a success. Whitehead Scientific and the South African Medical Research Council also played a major role in the success of the workshop. The local organising committee consisted of Dr Martin Nyaga (host, convener and chair), Dr Saheed Sabiu (secretary), and Mr Stephanus Riekert (principal ICT support).

News Archive

A model of resilience – Dr Anja Botha probes into the ability to recover from trauma
2014-12-02

She may have been awarded her doctorate degree only in July 2014, but Psychology lecturer at the University of the Free State (UFS), Dr Anja Botha, is already making a name for herself with her latest research.

Her study aims to develop a model of resilience for South African adolescents exposed to trauma. “The broad field, within which I work, is that of Developmental Psychology, with a specific focus on child and adolescent development and therapy,” says Dr Botha. 

Resilience studies are situated within Developmental Psychology since normal developmental tasks – such as achieving self-confidence and building supportive relationships – contribute greatly to children’s resilience. Resilience broadly refers to the individual’s ability to ‘bounce back’ after being exposed to adversity.

“The model of resilience which I compiled was a good fit for my participant group, indicating that the model explains the development of resilience in these adolescents well. The factors that I found to promote resilience in the South African context include various coping skills, intra- and interpersonal strengths, family involvement, and school engagement.

“Thus, aside from my passion for resilience studies, I am also very much interested in coping, strength-based interventions, parental guidance and school-based programmes.”

Dr Botha was awarded a Donald J Cohen fellowship in August 2014 during the 21st World Congress of the International Association for Child and Adolescent Psychiatrists and Allied Professions. The fellowship is in recognition of her work as an emerging international scholar in the field of child and adolescent mental health. This award was based on both her research as well as her involvement in the training of postgraduate students in child psychology.

She is currently supervising a number of master’s students’ research on various constructs related to resilience.

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