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19 July 2018 Photo Supplied
AEVGI advances Next-Generation Sequencing in Africa
Prof George Armah, Noguchi Memorial Institute for Medical Research, Ghana; Prof Carl Kirkwood, Bill and Melinda Gates Foundation, USA; Cornelius Hagenmeier, Director: Internationalisation, UFS; Prof Gert van Zyl, Dean: Health Sciences; Dr Martin Nyaga, Senior Lecturer in the NGS Unit; Prof Joyce Tsoka-Gwegweni, Vice-Dean: Health Sciences; Dr Glen Taylor, Senior Director: Research and Development; Prof Jeffrey Mphahlele, Vice-President, South African Medical Research Council.

The inaugural edition of the University of the Free State (UFS) Next-Generation Sequencing (NGS) Data and Bioinformatics Workshop, hosted by the UFS-NGS Unit in the UFS Faculty of Health Sciences, marked a new beginning for the advancement of NGS in Africa under the auspices of the African Enteric Viruses Genome Initiative (AEVGI), which was recently funded by the Bill and Melinda Gates Foundation.

The AEVGI will generate rotavirus genomes at the UFS-NGS Unit to investigate the long-term effects of the introduction of the monovalent RV1 vaccine in three African countries – Ghana, Malawi, and South Africa.

The workshop attracted over 90 participants from 15 national and international institutions, with organisations from seven different countries as well as company representatives attending the event. The workshop kicked off with a courtesy call to the Rector and Vice-Chancellor, Prof Francis Petersen, followed by a stakeholder meeting with the executive management of the UFS.

The funding was secured through an award to the principal investigator, Dr Martin Nyaga, and sub-awards to co-investigators, Dr Khuzwayo Jere, Dr Francis Dennis, and Dr Valentine Ndze. According to attendee evaluations of the workshop, the remarkable performance of the workshop instructors was outstanding. Through practical sessions, participants were equipped with knowledge on how to apply several tools of genetic data analysis, using the rotavirus genome as a model to construct and interpret different genomic datasets.

A total of 65 students attended the hands-on workshop, the majority of which were from South African higher-education institutions. The organisers are grateful to the sponsors, particularly to the Bill and Melinda Gates Foundation and the University of the Free State, for making the workshop a success. Whitehead Scientific and the South African Medical Research Council also played a major role in the success of the workshop. The local organising committee consisted of Dr Martin Nyaga (host, convener and chair), Dr Saheed Sabiu (secretary), and Mr Stephanus Riekert (principal ICT support).

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"Studies indicate disability, poverty and inaccessibility to healthcare are intricately linked " - expert opinion by Dr Magteld Smith
2014-12-03

Dr Magteld Smith

Programmes worldwide attempt to improve the lives of people with disabilities, but recent studies indicated that disability and poverty, as well as disability and the inaccessibility of health care, continues to go hand in hand.

In South Africa, and even in developed countries, research shows that people with disabilities achieve lower levels of education with higher unemployment rates, live in extreme poverty and have low living standards.

“To have a disability can therefore become a huge financial burden on either the disabled person, the family or caregivers,” says Dr Magteld Smith from the Department of Otorhinolaryngology.

She devotes her research to the medical-social model of the global organisation, the International Classification of Functioning, Disabilities and Health, focusing on all areas of deafness.

Furthermore, Dr Smith says it is more difficult or more expensive for people with disabilities to obtain insurance, because of the risks associated with disability.

Dr Smith also emphasises the inaccessibility and even unavailability of medical services or health care for people with disabilities.

“Services such as psychiatry or social services are often not accessible. When such services are available, it is not affordable for most people with disabilities.”

Dr Smith uses the example of a person who was born deaf:

“Doctors have limited knowledge of the different types of hearing impairments or how to read and interpret an audiogram. Very little understanding also exists for the impact of deafness on the person’s daily life.”

Dr Smith, who is deaf herself, describes the emotional state of mind of people with disabilities as a daily process of adjustment and self-evaluation.

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