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19 July 2018 Photo Supplied
AEVGI advances Next-Generation Sequencing in Africa
Prof George Armah, Noguchi Memorial Institute for Medical Research, Ghana; Prof Carl Kirkwood, Bill and Melinda Gates Foundation, USA; Cornelius Hagenmeier, Director: Internationalisation, UFS; Prof Gert van Zyl, Dean: Health Sciences; Dr Martin Nyaga, Senior Lecturer in the NGS Unit; Prof Joyce Tsoka-Gwegweni, Vice-Dean: Health Sciences; Dr Glen Taylor, Senior Director: Research and Development; Prof Jeffrey Mphahlele, Vice-President, South African Medical Research Council.

The inaugural edition of the University of the Free State (UFS) Next-Generation Sequencing (NGS) Data and Bioinformatics Workshop, hosted by the UFS-NGS Unit in the UFS Faculty of Health Sciences, marked a new beginning for the advancement of NGS in Africa under the auspices of the African Enteric Viruses Genome Initiative (AEVGI), which was recently funded by the Bill and Melinda Gates Foundation.

The AEVGI will generate rotavirus genomes at the UFS-NGS Unit to investigate the long-term effects of the introduction of the monovalent RV1 vaccine in three African countries – Ghana, Malawi, and South Africa.

The workshop attracted over 90 participants from 15 national and international institutions, with organisations from seven different countries as well as company representatives attending the event. The workshop kicked off with a courtesy call to the Rector and Vice-Chancellor, Prof Francis Petersen, followed by a stakeholder meeting with the executive management of the UFS.

The funding was secured through an award to the principal investigator, Dr Martin Nyaga, and sub-awards to co-investigators, Dr Khuzwayo Jere, Dr Francis Dennis, and Dr Valentine Ndze. According to attendee evaluations of the workshop, the remarkable performance of the workshop instructors was outstanding. Through practical sessions, participants were equipped with knowledge on how to apply several tools of genetic data analysis, using the rotavirus genome as a model to construct and interpret different genomic datasets.

A total of 65 students attended the hands-on workshop, the majority of which were from South African higher-education institutions. The organisers are grateful to the sponsors, particularly to the Bill and Melinda Gates Foundation and the University of the Free State, for making the workshop a success. Whitehead Scientific and the South African Medical Research Council also played a major role in the success of the workshop. The local organising committee consisted of Dr Martin Nyaga (host, convener and chair), Dr Saheed Sabiu (secretary), and Mr Stephanus Riekert (principal ICT support).

News Archive

Dr Abdon Atangana cements his research globally by solving fractional calculus problem
2014-12-03

 

Dr Abdon Atangana

To publish 29 papers in respected international journals – and all of that in one year – is no mean feat. Postdoctoral researcher Abdon Atangana at the Institute for Groundwater Studies at the University of the Free State (UFS) reached this mark by October 2014, shortly before his 29th birthday.

His latest paper, ‘Modelling the Advancement of the Impurities and the Melted Oxygen concentration within the Scope of Fractional Calculus’, has been accepted for publication by the International Journal of Non-Linear Mechanics.

In previously-published research he solved a problem in the field of fractional calculus by introducing a fractional derivative called ‘Beta-derivative’ and its anti-derivative called ‘Atangana-Beta integral’, thereby cementing his research in this field.

Dr Atangana, originally from Cameroon, received his PhD in Geohydrology at the UFS in 2013. His research interests include:
• the theory of fractional calculus;
• modelling real world problems with fractional order derivatives;
• applications of fractional calculus;
• analytical methods for partial differential equations;
• analytical methods for ordinary differential equations;
• numerical methods for partial and ordinary differential equations; and
• iterative methods and uncertainties modelling.

Dr Atangana says that, “Applied mathematics can be regarded as the bridge between theory and practice. The use of mathematical tools for solving real world problems is as old as creation itself. As written in the book Genesis ‘And God saw the light, that it was good; and divided the light from the darkness’, the word division appears here as the well-known method of separation of variables, this method is usually employed to solve a class of linear partial differential equations”.

“A mathematical model is a depiction of a system using mathematical concepts and language. The procedure of developing a mathematical model is termed mathematical modelling. Mathematical models are used not only in natural sciences, but also in social sciences such as economics, psychology, sociology and political sciences. These models help to explain systems and to study the effects of different components, and to make predictions about behaviours.”

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