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19 July 2018 Photo Supplied
AEVGI advances Next-Generation Sequencing in Africa
Prof George Armah, Noguchi Memorial Institute for Medical Research, Ghana; Prof Carl Kirkwood, Bill and Melinda Gates Foundation, USA; Cornelius Hagenmeier, Director: Internationalisation, UFS; Prof Gert van Zyl, Dean: Health Sciences; Dr Martin Nyaga, Senior Lecturer in the NGS Unit; Prof Joyce Tsoka-Gwegweni, Vice-Dean: Health Sciences; Dr Glen Taylor, Senior Director: Research and Development; Prof Jeffrey Mphahlele, Vice-President, South African Medical Research Council.

The inaugural edition of the University of the Free State (UFS) Next-Generation Sequencing (NGS) Data and Bioinformatics Workshop, hosted by the UFS-NGS Unit in the UFS Faculty of Health Sciences, marked a new beginning for the advancement of NGS in Africa under the auspices of the African Enteric Viruses Genome Initiative (AEVGI), which was recently funded by the Bill and Melinda Gates Foundation.

The AEVGI will generate rotavirus genomes at the UFS-NGS Unit to investigate the long-term effects of the introduction of the monovalent RV1 vaccine in three African countries – Ghana, Malawi, and South Africa.

The workshop attracted over 90 participants from 15 national and international institutions, with organisations from seven different countries as well as company representatives attending the event. The workshop kicked off with a courtesy call to the Rector and Vice-Chancellor, Prof Francis Petersen, followed by a stakeholder meeting with the executive management of the UFS.

The funding was secured through an award to the principal investigator, Dr Martin Nyaga, and sub-awards to co-investigators, Dr Khuzwayo Jere, Dr Francis Dennis, and Dr Valentine Ndze. According to attendee evaluations of the workshop, the remarkable performance of the workshop instructors was outstanding. Through practical sessions, participants were equipped with knowledge on how to apply several tools of genetic data analysis, using the rotavirus genome as a model to construct and interpret different genomic datasets.

A total of 65 students attended the hands-on workshop, the majority of which were from South African higher-education institutions. The organisers are grateful to the sponsors, particularly to the Bill and Melinda Gates Foundation and the University of the Free State, for making the workshop a success. Whitehead Scientific and the South African Medical Research Council also played a major role in the success of the workshop. The local organising committee consisted of Dr Martin Nyaga (host, convener and chair), Dr Saheed Sabiu (secretary), and Mr Stephanus Riekert (principal ICT support).

News Archive

Visiting Professor, Piet Bracke, Speaks on Public Mental Health
2015-02-20

Piet Bracke

Professor in the Department of Sociology at the Ghent University in Belgium, Piet Bracke, recently visited the UFS to speak about his research on the Public mental health and comparative health research: between social theory and psychiatric epidemiology.

At the public lecture on Monday 16 February, Bracke stated that part of the sociological attention to mental health and well-being was rooted in the 19th century's romanticists' discontent with self and society. The classical and contemporary social theorists' views on the disconnection between culture and the ‘real’ self resembles the more recent evolutionary psychological assumptions about the maladaptation of  psychobiological mechanisms to contemporary societal arrangements.

In contrast to these perspectives, contemporary psychiatric epidemiological research has a strongly underdeveloped conception about the nexus between society and population mental health. Both perspectives, the social-theory-and-societal-discontent approach and the biomedical psychiatric epidemiological approach, have drawbacks. Starting from the pitfalls of the aforementioned perspectives, they have been exploring the challenges posed by the development of a macro-sociology of population mental health.

Recently, this research domain has received renewed attention of scholars inside as well as outside sociology. The rise of multi-country, multilevel datasets containing health-related information, as well as the growing attention on the fundamental social causes of health and illness, and the focus on population as opposed to individual health, has contributed to the revival of comparative public mental health research. Based on findings from their recent research, they have illustrated how taking the context into account is vital when exploring the social roots of mental health and illness. In addition, they have demonstrated how they can liberate a few so-called ‘control variables’ in risk factor epidemiology – e.g. gender, education, and age – from their suppressed status by linking them to core concepts of sociology. With their research, they hope to further the development of a macro-sociology of public mental health.

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