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19 July 2018 Photo Supplied
AEVGI advances Next-Generation Sequencing in Africa
Prof George Armah, Noguchi Memorial Institute for Medical Research, Ghana; Prof Carl Kirkwood, Bill and Melinda Gates Foundation, USA; Cornelius Hagenmeier, Director: Internationalisation, UFS; Prof Gert van Zyl, Dean: Health Sciences; Dr Martin Nyaga, Senior Lecturer in the NGS Unit; Prof Joyce Tsoka-Gwegweni, Vice-Dean: Health Sciences; Dr Glen Taylor, Senior Director: Research and Development; Prof Jeffrey Mphahlele, Vice-President, South African Medical Research Council.

The inaugural edition of the University of the Free State (UFS) Next-Generation Sequencing (NGS) Data and Bioinformatics Workshop, hosted by the UFS-NGS Unit in the UFS Faculty of Health Sciences, marked a new beginning for the advancement of NGS in Africa under the auspices of the African Enteric Viruses Genome Initiative (AEVGI), which was recently funded by the Bill and Melinda Gates Foundation.

The AEVGI will generate rotavirus genomes at the UFS-NGS Unit to investigate the long-term effects of the introduction of the monovalent RV1 vaccine in three African countries – Ghana, Malawi, and South Africa.

The workshop attracted over 90 participants from 15 national and international institutions, with organisations from seven different countries as well as company representatives attending the event. The workshop kicked off with a courtesy call to the Rector and Vice-Chancellor, Prof Francis Petersen, followed by a stakeholder meeting with the executive management of the UFS.

The funding was secured through an award to the principal investigator, Dr Martin Nyaga, and sub-awards to co-investigators, Dr Khuzwayo Jere, Dr Francis Dennis, and Dr Valentine Ndze. According to attendee evaluations of the workshop, the remarkable performance of the workshop instructors was outstanding. Through practical sessions, participants were equipped with knowledge on how to apply several tools of genetic data analysis, using the rotavirus genome as a model to construct and interpret different genomic datasets.

A total of 65 students attended the hands-on workshop, the majority of which were from South African higher-education institutions. The organisers are grateful to the sponsors, particularly to the Bill and Melinda Gates Foundation and the University of the Free State, for making the workshop a success. Whitehead Scientific and the South African Medical Research Council also played a major role in the success of the workshop. The local organising committee consisted of Dr Martin Nyaga (host, convener and chair), Dr Saheed Sabiu (secretary), and Mr Stephanus Riekert (principal ICT support).

News Archive

Shimlas now second on Varsity Cup log
2015-02-25

After scoring nine tries to none to establish a 57-0 win over the Central University of Technology’s (CUT) Ixias in round three of the 2015 Varsity Cup Rugby Tournament, the UFS Shimlas are now second on the overall log.

Despite thunder showers in Bloemfontein on the evening of Monday 23 February, the match at the CUT Rugby Stadium continued. Shimlas’ Arthur Williams opened the scoreboard early with the first try of the evening, after getting his hands on a loose ball to break through the CUT defense line. Only four minutes later, Shimlas’ flank Gerhard Olivier scored another try. Both of these tries were successfully converted by Niel Marais, putting Shimlas in a 16-0 lead within less than seven minutes.

By halftime, the Shimlas’ lead had increased to 39-0. Daniel Maartens started the second-half scoring for the UFS when he crossed the try line in the 46th minute to secure Shimlas’ seventh try. After another successful conversion kick by Marais, the scoreboard read 47-0.

The match began to lose its spark as handling errors and ill-discipline became the order of the day. CUT were reduced to 14 men for the second time in the match, when Boetie Makethlo was sent to the sin bin in the 75th minute for an infringement at the breakdown, inches away from his try line.

Maartens went over the try line again in the 78th minute, scoring Shimlas’ eighth try in the match and taking his team’s score beyond the 50 mark. Shimlas managed yet another try in the last minute, with Niell Jordaan diving over the try line for old time’s sake.

Although the Shimlas’ 2015 Varsity Cup started off with a 29-29 draw against the University of Pretoria’s Tuks in Bloemfontein, they returned the following week to clinch a 24-0 win against the University of Johannesburg at the UJ Stadium. Apart from Tuks, who is at this stage on top of the log, no team has scored against Shimlas thus far in the 2015 Varsity Cup.

Up next, Shimlas will face the Stellenbosch University’s Maties side at Shimla Park in Bloemfontein for round four of the tournament on Monday 2 March 2015.

Our Player that Rocks: Niell Jordaan

Shimlas’ point scorers:

Tries: Arthur Williams, Gerhard Olivier (2), Marco Klopper, Vuyani Maqina (2), Daniel Maartens (2), Niell Jordaan
Conversion kicks: Niel Marais 4

 

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