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19 July 2018 Photo Supplied
AEVGI advances Next-Generation Sequencing in Africa
Prof George Armah, Noguchi Memorial Institute for Medical Research, Ghana; Prof Carl Kirkwood, Bill and Melinda Gates Foundation, USA; Cornelius Hagenmeier, Director: Internationalisation, UFS; Prof Gert van Zyl, Dean: Health Sciences; Dr Martin Nyaga, Senior Lecturer in the NGS Unit; Prof Joyce Tsoka-Gwegweni, Vice-Dean: Health Sciences; Dr Glen Taylor, Senior Director: Research and Development; Prof Jeffrey Mphahlele, Vice-President, South African Medical Research Council.

The inaugural edition of the University of the Free State (UFS) Next-Generation Sequencing (NGS) Data and Bioinformatics Workshop, hosted by the UFS-NGS Unit in the UFS Faculty of Health Sciences, marked a new beginning for the advancement of NGS in Africa under the auspices of the African Enteric Viruses Genome Initiative (AEVGI), which was recently funded by the Bill and Melinda Gates Foundation.

The AEVGI will generate rotavirus genomes at the UFS-NGS Unit to investigate the long-term effects of the introduction of the monovalent RV1 vaccine in three African countries – Ghana, Malawi, and South Africa.

The workshop attracted over 90 participants from 15 national and international institutions, with organisations from seven different countries as well as company representatives attending the event. The workshop kicked off with a courtesy call to the Rector and Vice-Chancellor, Prof Francis Petersen, followed by a stakeholder meeting with the executive management of the UFS.

The funding was secured through an award to the principal investigator, Dr Martin Nyaga, and sub-awards to co-investigators, Dr Khuzwayo Jere, Dr Francis Dennis, and Dr Valentine Ndze. According to attendee evaluations of the workshop, the remarkable performance of the workshop instructors was outstanding. Through practical sessions, participants were equipped with knowledge on how to apply several tools of genetic data analysis, using the rotavirus genome as a model to construct and interpret different genomic datasets.

A total of 65 students attended the hands-on workshop, the majority of which were from South African higher-education institutions. The organisers are grateful to the sponsors, particularly to the Bill and Melinda Gates Foundation and the University of the Free State, for making the workshop a success. Whitehead Scientific and the South African Medical Research Council also played a major role in the success of the workshop. The local organising committee consisted of Dr Martin Nyaga (host, convener and chair), Dr Saheed Sabiu (secretary), and Mr Stephanus Riekert (principal ICT support).

News Archive

Shimlas still the only unbeaten side in 2015 Varsity
2015-03-18

The Shimlas remain the only unbeaten side in this year’s Varsity Cup rugby tournament after their bonus-point 44-24 win against the University of Cape Town Ikeys in Bloemfontein.

The home side managed a very comfortable 34-8 lead in the first half against the defending champions Ikeys. No matter how hard the Ikeys fought back, the Shimlas win was inevitable, and secured the first ever home semifinal at the UFS.

It was in the second minute that Shimlas’ Gerhard Olivier went over the try line. The Shimlas continued to press forward, and kept the game play primarily in the UCT half of the field. By the time the first Strategy Break came along, the Shimlas already had a 21-0 lead over their visitors. The Ikeys did manage one converted try before halftime, still leaving the home side with  a 34-8 lead.

After halftime, there was still no stopping the Shimlas. Even when UCT’s attempt at a comeback saw them scoring their second converted try, the point difference were still 18 points. Shortly after, Olivier scored his third try for the Shimlas. The Ikeys’ response to this was scoring a third try in their comeback effort, putting the scoreboard at 39-24 with Shimlas still in the lead after 65 minutes.

Despite Ikeys’ attempt for their bonus point try near fulltime, Shimlas’ counter-attack saw their replacement player Boela Venter cross the try line for the last  time to secure a 44-24 win for the home side.

The Shimlas will host North-West University’s Pukke side at Shimla Park in the last round of the tournament this coming Monday. For the first time since the Varsity Cup’s inauguration in 2008, the UFS side has already secured a home semifinal for the week after.

Shimlas point scorers:

Tries: Gerhard Olivier (3), Johan van der Hoogt, Danie Maartens (2), Boela Venter
Conversion kicks: Niel Marais (3)

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