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19 July 2018 Photo Supplied
AEVGI advances Next-Generation Sequencing in Africa
Prof George Armah, Noguchi Memorial Institute for Medical Research, Ghana; Prof Carl Kirkwood, Bill and Melinda Gates Foundation, USA; Cornelius Hagenmeier, Director: Internationalisation, UFS; Prof Gert van Zyl, Dean: Health Sciences; Dr Martin Nyaga, Senior Lecturer in the NGS Unit; Prof Joyce Tsoka-Gwegweni, Vice-Dean: Health Sciences; Dr Glen Taylor, Senior Director: Research and Development; Prof Jeffrey Mphahlele, Vice-President, South African Medical Research Council.

The inaugural edition of the University of the Free State (UFS) Next-Generation Sequencing (NGS) Data and Bioinformatics Workshop, hosted by the UFS-NGS Unit in the UFS Faculty of Health Sciences, marked a new beginning for the advancement of NGS in Africa under the auspices of the African Enteric Viruses Genome Initiative (AEVGI), which was recently funded by the Bill and Melinda Gates Foundation.

The AEVGI will generate rotavirus genomes at the UFS-NGS Unit to investigate the long-term effects of the introduction of the monovalent RV1 vaccine in three African countries – Ghana, Malawi, and South Africa.

The workshop attracted over 90 participants from 15 national and international institutions, with organisations from seven different countries as well as company representatives attending the event. The workshop kicked off with a courtesy call to the Rector and Vice-Chancellor, Prof Francis Petersen, followed by a stakeholder meeting with the executive management of the UFS.

The funding was secured through an award to the principal investigator, Dr Martin Nyaga, and sub-awards to co-investigators, Dr Khuzwayo Jere, Dr Francis Dennis, and Dr Valentine Ndze. According to attendee evaluations of the workshop, the remarkable performance of the workshop instructors was outstanding. Through practical sessions, participants were equipped with knowledge on how to apply several tools of genetic data analysis, using the rotavirus genome as a model to construct and interpret different genomic datasets.

A total of 65 students attended the hands-on workshop, the majority of which were from South African higher-education institutions. The organisers are grateful to the sponsors, particularly to the Bill and Melinda Gates Foundation and the University of the Free State, for making the workshop a success. Whitehead Scientific and the South African Medical Research Council also played a major role in the success of the workshop. The local organising committee consisted of Dr Martin Nyaga (host, convener and chair), Dr Saheed Sabiu (secretary), and Mr Stephanus Riekert (principal ICT support).

News Archive

Fire as a management tool questionable in arid and semi-arid grassland areas
2015-03-24

Wild fire in the grassland
Photo: Supplied


The influence of fire on the ecosystem in the higher rainfall ‘‘sour’’ grassland areas of southern Africa has been well established. However, less information is available for arid and semi-arid ‘‘sweet’’ grassland areas, says Prof Hennie Snyman, Professor in the Department of Animal, Wildlife, and Grassland Sciences, about his research on the short-term impact of fire on the productivity of grasslands in semi-arid areas.

Sour and sweet grassland areas can be defined as receiving either higher or lower than approximately 600 mm of rainfall respectively. In quantifying the short-term impact of fire on the productivity of grasslands in semi-arid areas, a South African case study (experimental plot data) was investigated.

“Burned grassland can take at least two full growing seasons to recover in terms of above- and below-ground plant production and of water-use efficiency (WUE). The initial advantage in quality (crude protein) accompanying fire does not neutralise the reduction in half of the above-ground production and poor WUE occurring in the first season following the fire.

“The below-ground growth is more sensitive to burning than above-ground growth. Seasonal above-ground production loss to fire, which is a function of the amount and distribution of rainfall, can vary between 238 and 444 kg ha -1 for semi-arid grasslands. The importance of correct timing in the utilisation of burned semi-arid grassland, with respect to sustained high production, cannot be overemphasised,” said Prof Snyman.

In arid and semi-arid grassland areas, fire as a management tool is questionable if there is no specific purpose for it, as it can increase ecological and financial risk management in the short term.

Prof Snyman said: “More research is needed to quantify the impact of runaway fires on both productivity and soil properties, in terms of different seasonal climatic variations. The information to date may already serve as valuable guidelines regarding grassland productivity losses in semi-arid areas. These results can also provide a guideline in claims arising from unforeseen fires, in which thousands of rands can be involved, and which are often based on unscientific evidence.”

For more information or enquiries contact news@ufs.ac.za

 

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