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19 July 2018 Photo Supplied
AEVGI advances Next-Generation Sequencing in Africa
Prof George Armah, Noguchi Memorial Institute for Medical Research, Ghana; Prof Carl Kirkwood, Bill and Melinda Gates Foundation, USA; Cornelius Hagenmeier, Director: Internationalisation, UFS; Prof Gert van Zyl, Dean: Health Sciences; Dr Martin Nyaga, Senior Lecturer in the NGS Unit; Prof Joyce Tsoka-Gwegweni, Vice-Dean: Health Sciences; Dr Glen Taylor, Senior Director: Research and Development; Prof Jeffrey Mphahlele, Vice-President, South African Medical Research Council.

The inaugural edition of the University of the Free State (UFS) Next-Generation Sequencing (NGS) Data and Bioinformatics Workshop, hosted by the UFS-NGS Unit in the UFS Faculty of Health Sciences, marked a new beginning for the advancement of NGS in Africa under the auspices of the African Enteric Viruses Genome Initiative (AEVGI), which was recently funded by the Bill and Melinda Gates Foundation.

The AEVGI will generate rotavirus genomes at the UFS-NGS Unit to investigate the long-term effects of the introduction of the monovalent RV1 vaccine in three African countries – Ghana, Malawi, and South Africa.

The workshop attracted over 90 participants from 15 national and international institutions, with organisations from seven different countries as well as company representatives attending the event. The workshop kicked off with a courtesy call to the Rector and Vice-Chancellor, Prof Francis Petersen, followed by a stakeholder meeting with the executive management of the UFS.

The funding was secured through an award to the principal investigator, Dr Martin Nyaga, and sub-awards to co-investigators, Dr Khuzwayo Jere, Dr Francis Dennis, and Dr Valentine Ndze. According to attendee evaluations of the workshop, the remarkable performance of the workshop instructors was outstanding. Through practical sessions, participants were equipped with knowledge on how to apply several tools of genetic data analysis, using the rotavirus genome as a model to construct and interpret different genomic datasets.

A total of 65 students attended the hands-on workshop, the majority of which were from South African higher-education institutions. The organisers are grateful to the sponsors, particularly to the Bill and Melinda Gates Foundation and the University of the Free State, for making the workshop a success. Whitehead Scientific and the South African Medical Research Council also played a major role in the success of the workshop. The local organising committee consisted of Dr Martin Nyaga (host, convener and chair), Dr Saheed Sabiu (secretary), and Mr Stephanus Riekert (principal ICT support).

News Archive

Groundwater management vital for groundwater sustainability
2016-11-09

Description: Dr Yolanda Kotzé Tags: Dr Yolanda Kotzé

Dr Yolanda Kotzé, Affiliated Researcher in the
UFS Institute for Groundwater Studies, is passionate
about the management of groundwater.
Photo: Rulanzen Martin

An interest in groundwater resource management ignited the spark for a PhD research thesis by Dr Yolanda Kotzé, Affiliated Researcher in the Institute for Groundwater Studies (IGS) at the University of the Free State (UFS).

Her PhD research thesis titled, A Framework for Groundwater Use Authorisations as Part of Groundwater Governance in Water Scarce Areas within South Africa, was the result of her interest in groundwater resource management. Dr Kotzé identified the agricultural sector as one of the major water users, and a decision was made to conduct research within this sector.  

Research funded by Institute for Groundwater Studies
Groundwater is water found underground in cracks and spaces in soil, sand, and rocks. It is stored in, and moves slowly through geological formations of soil, sand, and rocks (aquifers). The National Department of Water and Sanitation was indirectly the client for this research. The research project was funded by the IGS. Given the current drought, effective groundwater resource management can be achieved within all sectors through sustainable abstraction and use without over-abstraction.

“Groundwater can be effectively managed
in the agricultural sector by sustainable use,
monitoring the quantity of groundwater use,
and measuring groundwater levels,”
said Dr Kotzé.

Research addresses improvement of groundwater management
Her promotor, mentor, teacher, and friend, the late Prof Gerrit van Tonder, introduced her to the field of Geohydrology, and especially to groundwater resource management. “With my research, I made a significant contribution to the improvement of groundwater governance and groundwater resource management, as well as to the handling of groundwater use authorisations for irrigation purposes in South Africa,” said Dr Kotzé. With this significant contribution, she attempts to address the phenomenon of poor groundwater allocation and groundwater resource management by means of a framework. The development of this framework has shown the value of action research in an attempt to find a solution to a problem. “Groundwater can be effectively managed in the agricultural sector by sustainable use, monitoring the quantity of groundwater use, and measuring groundwater levels,” said Dr Kotzé.

The methodology of the research consisted primarily of action research, which has a five-phase cyclical process. The research was Dr Kotzé’s application for a PhD in Geohydrology at the UFS in 2012. The research was completed in 2015.

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