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07 June 2018 Photo Prof CB Bousman, from Texas State University.
Quaternary International volume dedicated to UFS research fellow
Dr James Brink visits the Erfkroon site on the Modder River in the Free State.

The contents of a special issue of Quaternary International (QI), consisting of 13 articles and contributions by 45 authors (25 from abroad), was recently presented to Dr James Simpson Brink. The papers represent the broad range of topics covered by Dr Brink’s research interests.  

The special issue of QI was initiated to coincide with James Simpson Brink’s 60th birthday after he recently celebrated 35 years of ground-breaking research at the National Museum of Bloemfontein.

Dr Brink is affiliated to the Centre for Environmental Management at the University of the Free State (UFS).

Prof Louis Scott, researcher in the Department of Plant Sciences at the UFS, was the executive guest editor, and was part of a team of three guest editors (Dr Liora Horwitz from the Hebrew University in Jerusalem, and Dr Daryl Codron from the National Museum in Bloemfontein) who worked on this special issue of the journal, QI. 

In honour of a friend and colleague
“Dr Brink made contributions to osteology, Quaternary palaeontology, and archaeozoology, by investigating the environments and mechanisms that drove the evolution of mammal communities of southern Africa,” said the guest editors. 

“By studying the morphology of the endemic black wildebeest he demonstrated how the species evolved in the central interior of South Africa. He pioneered descriptions and dating of faunal assemblages that make up the so-called ‘Cornelian’ and ‘Florisian’ Land Mammal Ages. In this way he reconstructed the long history of environments in which Stone Age occupants survived in the region. The work included the age determination of the cranium with facial bones of an individual who lived at Floribad around 250 000 years ago.

Work enabled more important studies
“Dr Brink contributed more than purely academic insights in that he built and curated the modern mammal and fossil faunal collections of the Florisbad Quaternary Research Station. These collections made it possible for researchers, who came from all over the world, to visit the Free State and focus on spatial and temporal palaeoenvironmental trends. Apart from contributing to the functional diversity of mammalian species, this enabled the investigation of morphological and behavioural variations across populations and communities,” said the editors.

The topics of the papers in this special issue of QI are interdisciplinary and include different methods in archaeology, vertebrate palaeontology and past (or palaeo-) environmental reconstruction. The ages dealt with range from the relatively recent Iron Age to the Oldowan period, which is over a million years old.

According to Prof Scott, with a degree of overlap in the interdisciplinary fields studied, the papers can be arranged into 1) taphonomy and archaeozoology, relating to the processes resulting in the formation and preservation of fossil material in archaeological sites, 2) Stone Age archaeology, dealing with artefacts, stratigraphy and palaeoanthropology, and 3) palaeoecology, that includes palaeontology, isotope studies and palaeoenvironmental reconstructions.

The journal, published by Elsevier, will be distributed worldwide. 

News Archive

UFS cardiac team leading with project
2017-05-31

 Description: Cardiac team read more Tags: Cardiac team read more

Prof Peter Schultheiss of the Charité University in Berlin,
Germany, visited the Robert WM Frater Centre for
Cardiovascular Research at the UFS for a study regarding
cardiomyopathy, a significant cause of fatal heart failure
among Africans. From the left are Dr Glen Taylor,
Dr Danie Buys, Prof Makoali Makatoko,
Prof Schultheiss and Prof Francis Smit.
Photo: Rulanzen Martin

A team of cardiac doctors associated with the Robert WM Frater Cardiovascular Research Centre at the University of the Free State’s (UFS) Faculty of Health Sciences has commenced with a pioneering research project regarding idiopathic dilating cardiomyopathy.  

An Afrocentric research focus
Prof Francis Smit, Head of the Department of Cardiothoracic Surgery at the UFS and Head of the Frater Centre, describes dilating cardiomyopathy as a heart muscle disease that is quite common, particularly among people of African descent. The disease weakens the heart muscle, which in turn leads to heart failure.

“To date there is no curable treatment for this condition and 50% of patients that have shown heart failure, died within a period of five years. The causes of this condition have been unknown in the majority of patients. But over the past few years major strides have been made where virus infections of the heart muscle or myocarditis have been identified as a possible underlying cause. Various genetic diseases are also linked to it,” says Prof Smit.

International collaborations ensure success
According to Prof Smit, the project is being run in conjunction with Prof Heinz-Peter Schultheiss of the Charité University and the Institute for Cardiac Diagnostics and Therapy in Berlin, Germany.

“We have been working on the project over the past 18 months and I have twice visited Prof Schultheiss in Germany. He is now visiting us in Bloemfontein. We have established a collaborative project focused on patients in central South Africa”.
Prof Schultheiss is a world leader regarding the diagnosis, pathology and treatment of dilating cardiomyopathy, says Prof Smit.

“He brings a lifetime of research experience to Bloemfontein and is internationally renowned as the father of myocardial or heart muscle biopsies.

“His pioneering work on the discipline has led to diagnostic accuracy that has induced purposeful and personalised treatment of dilating cardiomyopathy and has brought about dramatic changes in some subsets of patients’ life expectancy and their cure.”

Solving problems close to home
According to Prof Mokoali Makatoko, Head of the Department of Cardiology, there are more than 1500 new cases of heart failure identified annually at the Universitas Academic Hospital, of which approximately 30% are attributed to cardiomyopathy. “With the use of endomyocardial biopsies the team hopes to treat viruses unique to Southern Africa as well as other underlying causes of dilating cardiomyopathy.”

Prof Stephen Brown, Head of Paediatric Cardiology at the Universitas Academic Hospital, says children suffering from this disease never reach a mature age and those under his supervision will also be undergoing these tests. Various other departments at the UFS will also participate in this project. Profs Makatoko and Brown did the first four endomyocardial biopsies under the management of Prof Schultheiss during the past week. The results will be available in the coming weeks after which the project will be officially launched and patient recruitment will start in earnest.

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