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12 June 2018 Photo Thabo Kessah
Young researcher to jet out to UK
Mamosa Ngcala who leaving for the United Kingdom on 31 July 2018.

When Mamosa Ngcala jets out to the United Kingdom (UK) on 31 July 2018, she will not only be doing research and improving herself academically at the Durham University, but she will also put yet another feather in the growing research profile cap of the Qwaqwa Campus.

“I am looking forward to my study visit under the mentorship of Dr Steve Chivasa, my supervisor’s co-researcher in the Department of Biosciences at the renowned Durham University. This will enable me to grow academically as much as it will get me closer to concluding my research on climate change and food security,” said Mamosa, a master’s student in Science (Botany). Her supervisor is Dr Rudo Ngara.

“Going there will fast-track my research that looks at how food security can be enhanced in as far as growing sorghum is concerned. This study in Plant Biotechnology aims to identify heat responsive genes in sorghum, which is the fifth most important cereal crop in the world. The information obtained in this study will serve as fundamental knowledge regarding molecular responses of plants to heat stress and will be used in breeding programmes to develop crops that can tolerate high temperature stress conditions caused by climate change, thus resulting in high crop yield in agriculture as well as food security,” she said. She will be in the UK until 12 September 2018.

Mamosa has recently won the 3-Minute thesis competition for graduates that was part of the ‘Sorghum in the 21st Century’ international conference held in Cape Town.

Talking about this achievement, she said: “Going head-to-head with PhD students from all over the world gave me extra motivation and drive to do well, and I did. This goes to show that we can achieve whatever we put our minds to. Having to summarise my entire study in three minutes for a non-specialist audience, using one PowerPoint slide, was a challenge that had to be overcome,” said Mamosa. The conference was organised by the Collaborative Research on Sorghum and Millet and the University of Pretoria.

Mamosa graduated with distinction in Botany for her honours degree. She is a member of the Golden Key International Honour Society and Chairperson of the Postgraduate Student Council and is looking forward to advancing her studies to PhD level.

News Archive

UFS cardiac team leading with project
2017-05-31

 Description: Cardiac team read more Tags: Cardiac team read more

Prof Peter Schultheiss of the Charité University in Berlin,
Germany, visited the Robert WM Frater Centre for
Cardiovascular Research at the UFS for a study regarding
cardiomyopathy, a significant cause of fatal heart failure
among Africans. From the left are Dr Glen Taylor,
Dr Danie Buys, Prof Makoali Makatoko,
Prof Schultheiss and Prof Francis Smit.
Photo: Rulanzen Martin

A team of cardiac doctors associated with the Robert WM Frater Cardiovascular Research Centre at the University of the Free State’s (UFS) Faculty of Health Sciences has commenced with a pioneering research project regarding idiopathic dilating cardiomyopathy.  

An Afrocentric research focus
Prof Francis Smit, Head of the Department of Cardiothoracic Surgery at the UFS and Head of the Frater Centre, describes dilating cardiomyopathy as a heart muscle disease that is quite common, particularly among people of African descent. The disease weakens the heart muscle, which in turn leads to heart failure.

“To date there is no curable treatment for this condition and 50% of patients that have shown heart failure, died within a period of five years. The causes of this condition have been unknown in the majority of patients. But over the past few years major strides have been made where virus infections of the heart muscle or myocarditis have been identified as a possible underlying cause. Various genetic diseases are also linked to it,” says Prof Smit.

International collaborations ensure success
According to Prof Smit, the project is being run in conjunction with Prof Heinz-Peter Schultheiss of the Charité University and the Institute for Cardiac Diagnostics and Therapy in Berlin, Germany.

“We have been working on the project over the past 18 months and I have twice visited Prof Schultheiss in Germany. He is now visiting us in Bloemfontein. We have established a collaborative project focused on patients in central South Africa”.
Prof Schultheiss is a world leader regarding the diagnosis, pathology and treatment of dilating cardiomyopathy, says Prof Smit.

“He brings a lifetime of research experience to Bloemfontein and is internationally renowned as the father of myocardial or heart muscle biopsies.

“His pioneering work on the discipline has led to diagnostic accuracy that has induced purposeful and personalised treatment of dilating cardiomyopathy and has brought about dramatic changes in some subsets of patients’ life expectancy and their cure.”

Solving problems close to home
According to Prof Mokoali Makatoko, Head of the Department of Cardiology, there are more than 1500 new cases of heart failure identified annually at the Universitas Academic Hospital, of which approximately 30% are attributed to cardiomyopathy. “With the use of endomyocardial biopsies the team hopes to treat viruses unique to Southern Africa as well as other underlying causes of dilating cardiomyopathy.”

Prof Stephen Brown, Head of Paediatric Cardiology at the Universitas Academic Hospital, says children suffering from this disease never reach a mature age and those under his supervision will also be undergoing these tests. Various other departments at the UFS will also participate in this project. Profs Makatoko and Brown did the first four endomyocardial biopsies under the management of Prof Schultheiss during the past week. The results will be available in the coming weeks after which the project will be officially launched and patient recruitment will start in earnest.

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