Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
31 May 2018 Photo Anja Aucamp
Microbiology department receives Research Chair in Pathogenic Yeasts Prof Carlien Pohl-Albertyn
Prof Carlien Pohl-Albertyn, Professor in the Department of Microbial, Biochemical and Food Biotechnology


The National Research Foundation (NRF) recently approved a fifth research chair for the University of the Free State (UFS), the Research Chair in Pathogenic Yeasts. Prof Carlien Pohl-Albertyn from the Department of Microbial, Biochemical and Food Biotechnology, will be chairing this research chair. 

Activities of the Research Chair in Pathogenic Yeasts builds on existing research strengths and will contribute towards understanding pathobiology of medically significant pathogenic yeasts belonging to the genera Candida and Cryptococcus. 

According to Prof Pohl-Albertyn, the research group, established in 2014, is the only one in South African focusing on understanding the role of bioactive lipids in host-pathogen interaction as well as in the search for novel drug targets. The group brought together three principal investigators, Prof Pohl-Albertyn, Prof Koos Albertyn and Dr Olihile Sebolai, with knowledge regarding various virulence factors (including immunomodulatory metabolites) produced by the Candida and Cryptococcus as well as molecular biology of yeasts. Besides the three principal investigators, the group also includes five PhD students, nine MSc students, four BSc honours students as well as two postdoctoral fellows. 

Current projects of the group include the production of immunomodulatory compounds by the yeasts, finding novel targets for antifungal drugs and the interaction between the yeasts and different hosts using a variety of infection models. In addition, the interaction between pathogenic yeasts and other co-infecting pathogens is also being investigated. 

Why research on fungal infections?
“As a result of presently used treatments for diseases and HIV/Aids, and the advances in medical interventions, many diseases no longer pose a threat to humans and life expectancy is prolonged. However, this has also caused an increase in various opportunistic infections, and most of all, fungal infections.

“With an increase in the number of individuals sensitive to invasive fungal infections, yeasts have begun to be reported more frequently as pathogens (yeasts that can cause disease). Infections by pathogenic yeasts affect a wide variety of patients. Although most of them are immunosuppressed (including HIV positive) other underlying conditions may predispose people to such infections. These include extremes of age (premature infants and the elderly), diabetes, cancer and cystic fibroses. In addition, patients hospitalised in intensive care units, as well as patients undergoing major abdominal or thoracic surgery are at high risk of invasive candidiasis. Similarly, HIV/Aids, liver cirrhosis and immunosuppressive therapy are known risk factors for invasive cryptococcosis,” said Prof Pohl-Albertyn.

According to her an important hurdle in the treatment of invasive yeast infection is the emergence of drug resistance in these pathogens. Therefore, research into pathobiology, including new drug targets, as well as novel treatment options, is a necessity. 

In line with the UFS research strategy
The NRF call for research chairs, specifically aimed at female researchers at universities that currently have fewer than 15 research chairs, came out in May 2017.

The university considers the current SARChi Chairs and the possibility of future chairs as an integral and strategic initiative to increase its national and international standing through excellent academic and research leadership. A Research Chair in Pathogenic Yeasts is therefore an invaluable addition to the UFS Research Strategy. 

The Research Chair is for five years, and is renewable for three terms.

Microbiology from University of the Free State on Vimeo.

News Archive

UFS helps to renovate schools
2005-10-10

Photo gallery

About 250 hostel students of the University of the Free State's (UFS) main campus yesterday painted and renovated four schools in the black townships of Bloemfontein.  This was part of Kovsie Rag's new approach to be more directly involved with communities.

Students were transported with busses and performed tasks such as the painting of class rooms and outside walls and the cleaning and painting of gutters and window panes.  The painting was judged by a panel of judges, that included the Rector and Vice-Chancellor, Prof Frederick Fourie.  These points will contribute to the each hostel's final point in the Rag fund raising campaign for 2005/2006.

 

 

Some of the students who painted the gutters of Maboloka Primary School in Bochabelo were from the left Ms Tume Kowang (18) (first year student in B Accounting from NJ van der Merwe hostel); Ms  Gloria Mangwane (19) (third year student in B Sc Biochemy from NJ van der Merwe hostel); Ms Adri Ras (21) (second year student in Occupational Therapy from Emily Hobhouse hostel) and Ms Malandi Els (20) (third year student in B Exercise and Feeding from Emily Hobhouse hostel).

See attached media statement:

UFS Rag and Eimpa paints assist with upgrading of schools

The spirit of Ubuntu will this year be truly reflected in the University of the Free State’s (UFS) Rag community out reach programme when senior students from the 23 hostels on the Main Campus will visit four less-privileged schools in the Mangaung area on Saturday 8 October 2005 to assist these schools in the upgrading of facilities.

The same day (Saturday 8 October 2005) the UFS first year students will visit the neighbourhoods in Bloemfontein from 08:00-13:00 to raise funds on an Ubuntu donation lists for Rag 2005/2006.

The Ubuntu project was started about seven years ago and it has grown each year. In the past the project was associated with a fundraising leg and a hostel publicity leg.  This year the aim is to involve the community to demonstrate how important fundraising initiatives are to help those less-privileged. 
 
The schools that will be visited are Legae Intermediary School in Batho, Mothusi Primary School in Rocklands, and the Maboloka and Lesedi Primary Schools in Bochabelo.  The schools in the Manugaung area had until 31 August 2005 to complete a questionnaire identifying what assistance is needed.  The Rag office, with the help of professional consultants from Eimpa Paints, chose four schools and visited each one to determine material/s needed to complete the work. 

Eimpa Paints is a partner of the Ubuntu project and will be sponsoring all paint necessary to complete the work at the schools.  All other material/s needed will be supplied by the UFS Rag office.

The hostels are divided into project teams and will clean and paint gutters and window sills and paint the walls of classrooms and outside walls.  At Maboloka School for instance, a project team will also to paint a wall with colourful characters.

Media release
Issued by:  Lacea Loader
Media Representative
Tel:  (051) 401-2584
Cell:  083 645 2454
E-mail:  loaderl.stg@mail.uovs.ac.za
7 October 2005

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept