Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
31 May 2018 Photo Anja Aucamp
Microbiology department receives Research Chair in Pathogenic Yeasts Prof Carlien Pohl-Albertyn
Prof Carlien Pohl-Albertyn, Professor in the Department of Microbial, Biochemical and Food Biotechnology


The National Research Foundation (NRF) recently approved a fifth research chair for the University of the Free State (UFS), the Research Chair in Pathogenic Yeasts. Prof Carlien Pohl-Albertyn from the Department of Microbial, Biochemical and Food Biotechnology, will be chairing this research chair. 

Activities of the Research Chair in Pathogenic Yeasts builds on existing research strengths and will contribute towards understanding pathobiology of medically significant pathogenic yeasts belonging to the genera Candida and Cryptococcus. 

According to Prof Pohl-Albertyn, the research group, established in 2014, is the only one in South African focusing on understanding the role of bioactive lipids in host-pathogen interaction as well as in the search for novel drug targets. The group brought together three principal investigators, Prof Pohl-Albertyn, Prof Koos Albertyn and Dr Olihile Sebolai, with knowledge regarding various virulence factors (including immunomodulatory metabolites) produced by the Candida and Cryptococcus as well as molecular biology of yeasts. Besides the three principal investigators, the group also includes five PhD students, nine MSc students, four BSc honours students as well as two postdoctoral fellows. 

Current projects of the group include the production of immunomodulatory compounds by the yeasts, finding novel targets for antifungal drugs and the interaction between the yeasts and different hosts using a variety of infection models. In addition, the interaction between pathogenic yeasts and other co-infecting pathogens is also being investigated. 

Why research on fungal infections?
“As a result of presently used treatments for diseases and HIV/Aids, and the advances in medical interventions, many diseases no longer pose a threat to humans and life expectancy is prolonged. However, this has also caused an increase in various opportunistic infections, and most of all, fungal infections.

“With an increase in the number of individuals sensitive to invasive fungal infections, yeasts have begun to be reported more frequently as pathogens (yeasts that can cause disease). Infections by pathogenic yeasts affect a wide variety of patients. Although most of them are immunosuppressed (including HIV positive) other underlying conditions may predispose people to such infections. These include extremes of age (premature infants and the elderly), diabetes, cancer and cystic fibroses. In addition, patients hospitalised in intensive care units, as well as patients undergoing major abdominal or thoracic surgery are at high risk of invasive candidiasis. Similarly, HIV/Aids, liver cirrhosis and immunosuppressive therapy are known risk factors for invasive cryptococcosis,” said Prof Pohl-Albertyn.

According to her an important hurdle in the treatment of invasive yeast infection is the emergence of drug resistance in these pathogens. Therefore, research into pathobiology, including new drug targets, as well as novel treatment options, is a necessity. 

In line with the UFS research strategy
The NRF call for research chairs, specifically aimed at female researchers at universities that currently have fewer than 15 research chairs, came out in May 2017.

The university considers the current SARChi Chairs and the possibility of future chairs as an integral and strategic initiative to increase its national and international standing through excellent academic and research leadership. A Research Chair in Pathogenic Yeasts is therefore an invaluable addition to the UFS Research Strategy. 

The Research Chair is for five years, and is renewable for three terms.

Microbiology from University of the Free State on Vimeo.

News Archive

University community join hands in the walk for peace and justice
2016-03-02

Description: Prayer walk Callie Human Centre Tags: Prayer walk

The Campus Ministries Forum and South African Council of Churches (Free State) have organised a walk for peace and justice from the Main Building to the Callie Human Centre on the Bloemfontein Campus of the University of the Free State (UFS) on Tuesday 1 March 2016. This walk was followed by a prayer meeting at the Callie Human Centre.

Pastors from the Campus Ministries Forum of the South African Council of Churches (Free State) led a group of more than 350 students and staff in praise and worship, followed by prayers in English, Afrikaans, and Sesotho.

A significant gesture at the event was the church leader’s plea for peace and solutions for the conflict at the UFS.

Bishop Monty Mabale, Chairperson of the South African Council of Churches, read an extract from the declaration compiled by the pastors ministering to staff and students at the UFS.

“We are saddened by the violence and vandalism that took place on and off campus.  We understand that there are many reasons for frustration and anger, which lead to tensions at the end of last year and again now. We also understand that there are different perspectives on these developments and the complexities underlying to this. However, we cannot agree with the hate speech, the continuous blaming of others, the instigation of violence, and the damage being caused to this precious institution and its commitment to the ideal and practices of reconciliation and a proper education for every student.

“Because we believe in the justice and mercy of God in Christ, let us seek His justice in a compassionate way. Let us resolve to glorify his name in the way we enter into dignified discussions when addressing those matters we perceive to be injustices, and seek for solutions. Let us be critical of our own biased perceptions, opening ourselves to the practice of listening to the viewpoints of others and learning from each other, while discerning the will of God in our society together,” Bishop Mabale said.

The forum and council also wrote a special prayer for UFS students, staff, parents, and management:

Our Father in Heaven
•    You have created us all as unique, special people, each with a great destiny.
•    You have an awesome plan for our University, and value every person working and studying here.
•    We have not respected Your heart and opinion of everyone on campus, and so we have sinned against You.
•    Forgive us where we did not follow Your example of reconciliation, restoration, and forgiveness through the blood of Christ, Your Son, on the cross. We need You to show us what You expect of us: grace, mercy, respect, and tolerance for one another from a place of gratefulness and humility.
•    We are grateful for the opportunity and honour You have given us to be involved in this institution.
•    We repent and accept afresh Your commandment to love You and to love our neighbour as we love ourselves.
•    You are saying to us: “For I know the plans I have for you," declares the LORD, "plans to prosper you and not to harm you, plans to give you hope and a future.” We, as an institution, believe and receive this promise You gave to us.

In Jesus Name we pray,
Amen.

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept