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10 October 2018 | Story UFS | Photo Moeketsi Mogotsi
International Cultural Diversity Festival builds bridges
Global cuisines galore at the International Cultural Diversity Festival


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Celebrating our heritage allows us to learn about each other's cultures and traditions, and it is an activity that brings people together. "Heritage is an important element of our everyday lives that constantly reminds us of who we are and how far we have come," says Bonolo Makhalemele, International Cultural Diversity Festival organising team leader.

Cultivating intercultural connectivity

The Bloemfontein Campus was a hive of festivities as the community received cultural education from all over the world while being serenaded with diverse music, indulging in delicious cuisines, and dressed in ethic regalia at the festival hosted by the University of the Free State's (UFS) Office for International Affairs. Reinforcing unity and diversity formed the foundation of the theme: Building bridges in heritage - Connecting local and international cultures. Although it was a first for the UFS, the festival is an annual highlight on many countries' calendars, with the university intending to follow suit.

Makhalemele firmly believes that even in our uniqueness, there are immense similarities which we share and can celebrate. "Not only do we build bridges in celebrating our heritage, but we foster reconciliation, promote unity in diversity, and breathe life as well as meaning into our identities through the whole process." 

African artistic fashion


Busisiwe Ntsele, representing the House of Diva (HOD) which manufactures tailor-made Africa-inspired clothes for ladies of all sizes, manned one of the stalls at the festival. "We call it the House of Diva because it gives you the magical feeling of being an African woman," she said. Ntsele also shared the story of her cultural background, being born to South African parents as a child of the diaspora in the Kingdom of the Swati and growing up to marry a partner from Lesotho.

The Cultural Festival proved to be a successful infusion of food, fashion, dance, music, as well as arts and crafts from countries such as Lesotho, Zimbabwe, Zambia, Kenya, Swaziland, Cameroon, Kenya, Namibia, Malawi, Tanzania, Spain, Uganda, Argentina, Ghana, Ethiopia, China, Nigeria, Cuba, Bangladesh, India, Taiwan, Netherlands, Germany, the United States of America, Libya, Congo, Botswana, Mozambique, Ireland, Israel, Ivory Coast, Korea, France, Sudan, Angola, New Zealand, and Afghanistan.

Students, staff members, and the community had the opportunity to become interculturally competent, which is an essential skill within a transforming environment such as the university. 



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UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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