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26 October 2018
Dr Annamarie van Jaarsveld believes occupational therapy is important
Dr Annamarie van Jaarsveld believes occupational therapy is important for personal well-being.

On 27 October the profession of occupational therapy is promoted and celebrated internationally. The theme for this year is “Celebrating our global community.” Due to the theme of this year occupational therapists form all over the globe will be able to join in the World Federation for Occupational Therapy Virtual Exchange webinars.
 
Occupational therapy promotes health and well-being through occupation. The overarching goal of occupational therapy is to enable people to participate in the activities of everyday life that is meaningful to them. Occupational therapists work with people and communities in an effort to enable people of all ages to live life to its fullest by helping them maintain and/or promote health, and prevent (or live better with) injury, illness, or disability. 

Common occupational therapy interventions include helping children with disabilities to participate fully in school and social situations, helping people recovering from injury to regain skills, and providing supports for older adults experiencing physical and cognitive changes. Occupational and social justice along with occupational deprivation are core within the profession as it relates to oppression or restrictions to participation in occupation impacting on well-being and quality of life. 

Taking the lead in Sensory Integration research

Dr Annamarie van Jaarsveld is a lecturer in the Department of Occupational Therapy, and she is at the forefront of research in sensory integration, a specialist field within occupational therapy. Apart from completing her PhD on the curriculum design of a South African professional master’s degree qualification in sensory integration, she is also heading the South African leg of a large international study in collaboration with sensory integration experts all over the world.

Dr Van Jaarsveld explains: “The Evaluation of Ayres Sensory Integration (EASI) is a new test which aims to be a first of its kind in the field of sensory integration and occupational therapy. It will be inexpensive, electronically accessible and practical, and standardised on an international population which includes a South African sample. This will make the test accessible and useful for therapists in South Africa to be able to assess sensory integration related function of all South African children in a valid and reliable manner.” 

In addition to being the South African lead on the international EASI standardisation study, Annamarie was selected as the chairperson of the Board of Council Meetings of the International Council for Education in Ayres Sensory Integration (ICEASI). She is also the International Liaison on the board of the South African Institute for Sensory Integration. 

Annamarie’s passion for sensory integration and the application of a highly researched and specialised subfield where the expertise and guidance are provided by a first-world country is not only evident in her research, but also in various community projects that she is involved in. One such a project, Back to Urth Playgrounds, aims to make sensory integration relevant to the needs of South African children and their families struggling with sensory integration issues within the realities of diverse contexts. Through the designing of sustainable playgrounds based on sensory integration theory, building the playgrounds in collaboration with the community and other stakeholders, and equipping educators and caregivers with knowledge on how to encourage children to use the playgrounds, Annamarie has contributed to making the potential of sensory integration-based intervention accessible to the most under-resourced of areas. 

With the 27th of October being International Occupational Therapy Day, Annamarie says: “Sensory integration is not only the best researched field within occupational therapy, providing more and more best practice evidence through rigorous research, it is also becoming more available to children and families from all walks of life – indeed exciting times ahead for this field of practice and it remains a privilege to be involved in it”.  

News Archive

Cardiology Unit involved in evaluation of drug for rare genetic disease
2013-01-04

Front from the left, are: Marinda Karsten (study coordinator and registered nurse),
Laumarie de Wet (clinical technologist), Charmaine Krahenbuhl (study coordinator and radiographer),
Lorinda de Meyer (administrator), Andonia Page (study coordinator and enrolled nurse);
back Dr Gideon Visagie (sub investigator), Dr Derick Aucamp (sub investigagtor),
Prof. Hennie Theron, (principal investigator) and Dr Wilhelm Herbst (sub investigator).
Photo: Supplied
09 January 2013


The Cardiology Research Unit at the University of the Free State (UFS) contributed largely to the evaluation of the drug Juxtapid (lomitapide), which was developed by the Aegerion pharmaceutical company and approved by the FDA (Federal Drug Administration). Together with countries such as die USA, Canada and Italy, the UFS’ Unit recruited and evaluated the most patients (5 of 29) for the study since 2008.  

The drug was evaluated in persons with so-called familial homozygous hypercholesterolemia (HoFH).  

Following its approval by the FDA, Juxtapid is now a new treatment option for patients suffering from HoFH. The drug operates in a unique way which brings about dramatic improvements in cholesterol counts.  

According to Prof. Hennie Theron, Associate Professor in the Department of Cardiology at the UFS and Head of the Cardiology Contract Research Unit, HoFH is a serious, rare genetic disease which affects the function of the receptor responsible for the removal of low-density lipoprotein cholesterol (LDL-C) (“bad” cholesterol) from the body. Damage to the LDL receptor function leads to extremely high levels of blood cholesterol. HoFH patients often develop premature and progressive atherosclerosis, which is a narrowing or blockage of the arteries.  

“HoFH is a genetically transmitted disease and the most severe form of hypercholesterolemia. Patients often need a coronary artery bypass or/and aortic valve replacement before the age of 20. Mortality is extremely high and death often occurs before the third decade of life. Existing conventional cholesterol-lowering medication is unsuccessful in achieving normal target cholesterol values in this group of patients.  

“The only modality for treatment is plasmapheresis (similar to dialysis in patients with renal failure). Even with this type of therapy the results are relatively unsatisfactory because it is very expensive and the plasmapheresis has to be performed on a regular basis.  

“The drug Juxtapid, as currently evaluated, has led to a dramatic reduction in cholesterol values and normal values were achieved in several people. No existing drug is nearly as effective.  

“The drug represents a breakthrough in the treatment of familial homozygous hypercholesterolemia. The fact that it has been approved by the FDA, gives further impetus to the findings,” says Prof. Theron.  

In future further evaluation will be performed in other forms of hypocholesterolemia.  

According to Prof. Theron, the findings of the study, as well as the recent successful FDA evaluation, once again confirms the fact that the UFS’ Cardiology Contract Research Unit is doing outstanding work.  

Since its inception in 1992, the Unit has already been involved in more than 60 multi-centre, international phase 2 and 3 drug studies. Several of these studies, including the abovementioned study, really affected the way in which cardiology functions.  

The UFS’ Cardiology Contract Research Unit is being recognised nationally and internationally for its high quality of work and is constantly approached for their involvement in new studies.  

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