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31 December 2019
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Story Dr Cindé Greyling
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Photo Anja Aucamp
Dr Mariana Erasmus, SAENSE Platform Manager, says water remediation is vital for both the ecosystem and industries.
KovsieInnovation at the UFS supports innovative research outputs in various ways – one of which is to protect the intellectual property and to register patents where viable. This is in line with KovsieInnovation’s broader aim to create third-stream income for the university. Patent registration is a complex process and the UFS is proud to have the needed expertise to properly facilitate such an endeavour.
The SAENSE Platform
South Africa is a water-scarce country, with many water hungry industries (such as agriculture and mining). “Industrial processes often contaminate water with heavy metals, harmful chemicals, radioactive waste, and even organic sludge,” Dr Mariana Erasmus, SAENSE Platform Manager, explains.
Hence, water remediation is vital for both the ecosystem and industries. One of the key functions of the SAENSE Platform is to offer water-remedial solutions for the (bio)remediation of nitrates, heavy metals, and salts, among others. The platform’s activities and services are supported by undergraduate and postgraduate students and researchers, using Technology Innovation Agency (TIA) funding. TIA is a national public entity that serves as key institutional intervention to bridge the innovation chasm between research and development.
From waste to water
Through the joint effort of two mining companies and the UFS/TIA SAENSE Research Platform, a new treatment for mine drainage (MD) has been developed. This patented B-DAS (Barium – Dispersed Alkaline Substrate) technology effectively treats the major contaminants found in acid, alkaline, or neutral mining wastewater. The aim of the B-DAS system is to provide a passive water-treatment solution with minimum waste production; it can also be a potential pre-treatment for reverse osmosis (RO) to lower the requirements of the membranes and therefore potentially reduce the RO cost.
The success of the patent is that it turns unusable water into water that is fit for agricultural purposes at a reduced cost and increased efficiency.
New research informs improved treatment of brain inflammation
2017-10-13
Dr Adepemi Ogundeji, researcher in the Department of Microbial,
Biochemical and Food Biotechnology at the
University of the Free State,and Dr Olihile Sebolai,
her study leader from the same department.
Photo: Charl Devenish
Microbiologist Dr Adepemi Ogundeji has uncovered a new use for an old medicine that can potentially save lives and money. Under the guidance of her study leader, Dr Olihile Sebolai, Dr Ogundeji set out to fight a fungal disease caused by Cryptococcus neoformans. Drs Ogundeji and Sebolai are from the University of the Free State Department of Microbial, Biochemical and Food Biotechnology.
Dr Ogundeji is passionate about education. “My aim will always be to transfer knowledge and skills in the microbiology field,” she said. “Dr Ogundeji’s study is celebrated in that it found a new purpose for existing medicines. An advantage of repositioning old medicines is by-passing clinical trials, which sometimes take 20 years, and the safety of such medicines is already known,” Dr Sebolai, explained.
Cryptococcus infections are difficult to control and often lead to brain inflammation. In layman’s terms: “Your brain is on fire”. People with HIV/Aids are especially vulnerable, surviving only about three months without treatment. Such patients may present with a Cryptococcus-emergent psychosis, and some with an out-of-control inflammatory condition when initiated on ARVs.
Dr Ogundeji found that the clinically recommended dosage of aspirin (anti-inflammatory medicine), and quetiapine (anti-psychotic medicine) is sufficient to control the infection. Her exceptional work was readily published in some of the foremost journals in her field, namely, Antimicrobial Agents and Chemotherapy and Frontiers in Microbiology