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01 February 2019 | Story Zama Feni | Photo Charl Devenish
Disease Control and Prevention InStory
From left, seated: Dr Mathew Esona, CDC delegate; Dr Michael Bowen, CDC delegate; Dr Martin Nyaga, lead Researcher at the UFS-NGS Unit; standing: Mojalefa Buti, Office of the Vice-Dean, UFS Faculty of Health Sciences; Dr Glen Tylor, Senior Director, Directorate Research Development; Cornelius Hagenmeier, Director, Office for International Affairs; and Dr Saheed Sabiu, Postdoctoral Research Fellow in the Faculty of Natural and Agricultural Sciences.

In pursuit of efforts to advance research on viruses and disease control, the United States-based Centre for Disease Control and Prevention (CDC) has made a commitment to enhance the University of the Free State (UFS) Next Generation Sequencing (NGS) Unit’s data collection systems and further empower its staff and students.

UFS and US guests explore areas of mutual; cooperation

During a visit to the university in early December last year CDC delegation, Dr Michael Bowen and Dr Mathew Esona, a meeting was held with the lead Researcher at the UFS-NGS Unit, Dr Martin Nyaga; Senior Director of the UFS Directorate Research Development, Dr Glen Tylor; Director of UFS Office for International Affairs, Cornelius Hagenmeier; and Dr Saheed Sabiu Postdoctoral Research Fellow in the Faculty of Natural and Agriculture Sciences. It was in this meeting that areas of mutual collaboration and engagement between the two institutions which include technology transfer, funding and wet and dry laboratory quality control and capacity development were identified.

The UFS-NGS Unit, established in 2016, enjoys longstanding networking and collaborative ventures with renowned researchers in Africa, the USA, and Europe – which in return, have contributed immensely to the research activities of the university as a whole.

Dr Nyaga said in an effort to advance genomics research in the NGS Unit, the visitors have committed themselves to initiate and further enhance capacity development for the unit’s staff and students.

US guests impressed with advanced equipment at UFS

The CDC delegation were intrigued that the UFS also operates a Miseq Illumina platform like the one used at their enteric-viruses laboratory. It could thus be in line to assist in developing exclusive pipelines for the analysis of NGS data generated by the UFS-NGS Unit.

This is a personal sequencing system, which is a powerful state-of-the-art next-generation sequencer. It uses sequencing-by-synthesis technology capable of sequencing up to 15GB of high-quality filtered bases per run, with up to 600 base-pair read lengths. This allows the assembly of small genomes or the detection of target variants with unmatched accuracy, especially within homo-polymer regions.

UFS and CDC engagements still on

Further engagements about the identified areas of collaboration are ongoing between Hagenmeier, Dr Bowen, and Dr Nyaga, who are currently working on appropriate mechanisms to enact the envisaged collaboration between the two institutions.

The NGS Unit received research awards from the World Health Organisation, South African Medical Research Council, Poliomyelitis Research Foundation, and the National Research Foundation for different aspects of genomics research, and more recently from the Bill and Melinda Gates Foundation for the Enteric Viruses Genome Initiative, involving four African countries (South Africa, Ghana, Malawi, and Cameroon).

News Archive

Researcher transforms despair into diamonds
2016-01-18

PhD candidate, Lerato Machetela and some members of the group Diamonds in the Rough having some fun between rehearsals.

Awash in hopelessness, substance abuse, violence, and sexual promiscuity. This is the lived reality of the youth in Jagersfontein. But now Lerato Machetela is using her research to change it.

As a PhD candidate in Trauma, Forgiveness, and Reconciliation Studies at the University of the Free State (UFS), Machetela assembled a group of 14 young men – ranging between the ages of 9 and 18 – who call themselves Jagersfontein’s Diamonds in the Rough. Combining elements from psychology, education, and entertainment, Machetela has established a platform that grounds these young ones adrift in circumstances. By means of song and dance, these young ones have become grounded through creativity.

While discussing what it means to be free in the new South Africa, Machetela asked the group to come up with a song similar to the struggle song, ‘Nelson Mandela usi litheli ixolo’.

Jagersfontein’s Diamonds in the Rough Researcher, Lerato Machetela, combines psychology, education, and entertainment to ground local youths through creativity.

The result: He’s a teenager, but he drinks Hansa.

“This then developed into a dance routine depicting what the youth is doing with their freedom,” Machetela says. With each beat of their boots and rhythmic clap of their hands, the group illustrates the ways in which the youth has constructed – and come to understand – their daily realities. “The routine includes the expression of alcohol and drug abuse, and ends of with the importance of education.”

Through the creative expressions of Diamonds in the Rough, Machetela is able not only to explore the reality of the youth in Jagersfontein, but also to investigate intergenerational trauma. “I am looking at whether there is a relationship between these young people’s current circumstances and the experiences of their parents’ generation during the apartheid years. That is, what sort of meanings do they construct as young, black South Africans growing up in the new South Africa?”

What started off as a research project is now rippling beyond academic spheres, though. The Free State Department of Sport, Arts, Culture and Recreation has taken note of this initiative. As a result, the group has already performed at the Bloem Show, International Museums Day, and Heritage Day celebrations, as well as at the Mangaung African Cultural Festival (MACUFE).  

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