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01 February 2019 | Story Zama Feni | Photo Charl Devenish
Disease Control and Prevention InStory
From left, seated: Dr Mathew Esona, CDC delegate; Dr Michael Bowen, CDC delegate; Dr Martin Nyaga, lead Researcher at the UFS-NGS Unit; standing: Mojalefa Buti, Office of the Vice-Dean, UFS Faculty of Health Sciences; Dr Glen Tylor, Senior Director, Directorate Research Development; Cornelius Hagenmeier, Director, Office for International Affairs; and Dr Saheed Sabiu, Postdoctoral Research Fellow in the Faculty of Natural and Agricultural Sciences.

In pursuit of efforts to advance research on viruses and disease control, the United States-based Centre for Disease Control and Prevention (CDC) has made a commitment to enhance the University of the Free State (UFS) Next Generation Sequencing (NGS) Unit’s data collection systems and further empower its staff and students.

UFS and US guests explore areas of mutual; cooperation

During a visit to the university in early December last year CDC delegation, Dr Michael Bowen and Dr Mathew Esona, a meeting was held with the lead Researcher at the UFS-NGS Unit, Dr Martin Nyaga; Senior Director of the UFS Directorate Research Development, Dr Glen Tylor; Director of UFS Office for International Affairs, Cornelius Hagenmeier; and Dr Saheed Sabiu Postdoctoral Research Fellow in the Faculty of Natural and Agriculture Sciences. It was in this meeting that areas of mutual collaboration and engagement between the two institutions which include technology transfer, funding and wet and dry laboratory quality control and capacity development were identified.

The UFS-NGS Unit, established in 2016, enjoys longstanding networking and collaborative ventures with renowned researchers in Africa, the USA, and Europe – which in return, have contributed immensely to the research activities of the university as a whole.

Dr Nyaga said in an effort to advance genomics research in the NGS Unit, the visitors have committed themselves to initiate and further enhance capacity development for the unit’s staff and students.

US guests impressed with advanced equipment at UFS

The CDC delegation were intrigued that the UFS also operates a Miseq Illumina platform like the one used at their enteric-viruses laboratory. It could thus be in line to assist in developing exclusive pipelines for the analysis of NGS data generated by the UFS-NGS Unit.

This is a personal sequencing system, which is a powerful state-of-the-art next-generation sequencer. It uses sequencing-by-synthesis technology capable of sequencing up to 15GB of high-quality filtered bases per run, with up to 600 base-pair read lengths. This allows the assembly of small genomes or the detection of target variants with unmatched accuracy, especially within homo-polymer regions.

UFS and CDC engagements still on

Further engagements about the identified areas of collaboration are ongoing between Hagenmeier, Dr Bowen, and Dr Nyaga, who are currently working on appropriate mechanisms to enact the envisaged collaboration between the two institutions.

The NGS Unit received research awards from the World Health Organisation, South African Medical Research Council, Poliomyelitis Research Foundation, and the National Research Foundation for different aspects of genomics research, and more recently from the Bill and Melinda Gates Foundation for the Enteric Viruses Genome Initiative, involving four African countries (South Africa, Ghana, Malawi, and Cameroon).

News Archive

Twenty years of the constitution of South Africa – cause for celebration and reflection
2016-05-11

Description: Judge Azar Cachalia Tags: Judge Azar Cachalia

Judge Azar Cachalia

The University of the Free State’s Centre for Human Rights and the Faculty of Law held the celebration of the twentieth anniversary of the adoption of the South African Constitution on 11 May 2016 on the Bloemfontein Campus.  Students and faculty members celebrated and reflected on not only the achievements of the constitution but also on perspectives regarding its relevance in modern society, and to what extent it has upheld the human rights of all citizens of South Africa.

The panel discussion started with a presentation on the pre-1996 perspective by Judge Azar Cachalia of the Supreme Court of Appeal.  Judge Cachalia reflected on his role in the realisation and upholding of the constitution, from his days as a student activist, then as an attorney representing detainees during political turmoil, and currently as a judge: “My role as an attorney was to defend people arrested for public violence. My role as a judge today is to uphold the constitution.”  He stressed the importance of the constitution today, and the responsibility institutions such as the police service have in upholding human rights.  Judge Cachalia played a significant role in drafting the new Police Act around 1990, an Act which was to ensure that the offences perpetrated by the police during apartheid did not continue in the current democratic era. Further, he pointed out that societal turmoil has the potential to make society forget about the hard work that was put into structures upholding human rights. “Constitutions are drafted in moments of calm.  It is a living document, and we hope it is not torn up when we go through social conflict, such as we are experiencing at present.”

Thobeka Dywili, a Law student at the UFS, presented her views from the new generation’s perspective.  She relayed her experience as a student teaching human rights at schools in disadvantaged communities. She realised that, although the youth are quite aware of their basic human rights, after so many years of democracy, “women and children are still seen as previously disadvantaged when they should be equal”. She pointed out that, with the changing times, the constitution needs to be looked at with a new set of eyes, suggesting more robust youth engagement on topics that affect them, using technology to facilitate discussions. She said with the help of social media, it is possible for a simple discussion to become a revolution; #feesmustfall was a case in point.

Critical perspectives on the constitution were presented by Tsepo Madlingozi of University of Pretoria and University of London. In his view, the constitution has not affected policy to the extent that it should, with great disparities in our society and glaring issues, such as lack of housing for the majority of the poor.  “Celebration of the constitution should be muted, as the constitution is based on a decolonisation approach, and does not directly address the needs of the poor. The Constitutional Court is not pro-poor.”  He posed the question of whether twenty years on, the present government has crafted a new society successfully.  “We have moved from apartheid to neo-apartheid, as black elites assimilate into the white world, and the two worlds that exist have not been able to stand together as a reflection of what the constitution stands for.”

Prof Caroline Nicholson, Dean of the Faculty of Law, encouraged more open discussions, saying such dialogues are exactly what was intended by the Centre for Human Rights. She emphasised the importance of exchanging ideas, of allowing people to speak freely, and of sharing perspectives on important issues such as the constitution and human rights.

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