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23 January 2019 | Story Charlene Stanley | Photo Charlene Stanley
Michele Middle
Michelle Middle, CMO of Farmovs, looks forward to expanding their operations after the UFS acquired 100% shareholding in 2018.

In medical research, there are NO shortcuts.

The journey of a new medicine from lab to pharmacy shelf takes on average at least 10 years.

Michelle Middle’s journey from young medical graduate starting her first job at FARMOVS to becoming the company’s Chief Medical Officer, was more than twice that long. It was a journey that systematically and adequately equipped her to now Co-captain this flagship enterprise through its biggest challenge yet.

Michelle remembers how Farmovs started in 1974 as a research centre in the Department of Pharmacology. After graduating as medical doctor, she joined Farmovs in 1993, shortly before they moved to their current extensive facilities just south of the Sasol Library.

In 2000, international Clinical Research Organization (CRO) giant Parexel acquired a 70% shareholding, and the name changed to Farmovs-Parexel.

“Parexel really invested a lot in infrastructure and technology, bringing facilities here on par with the best in the world,” says Michelle.

Her own journey in medical research took her to George and later to the US and UK, where she held various international executive leadership positions in international companies.

When the UFS acquired a 100% shareholding in Farmovs earlier this year, she came full circle, as she returned to Bloemfontein to spearhead the expansion of patient studies in collaboration with the Faculty of Health Sciences.

“The opportunities we have here are really enormous,” says an excited Michelle.

“We are the only university in the country with this kind of infrastructure. Apart from our state-of-the-art bioanalytical lab, we also have facilities to accommodate close to 100 research participants. We now have 45 years’ experience in advanced medical research, plus established international clients. We can provide pharmaceutical companies with basically everything they need to develop new medicines.”

Another exciting development is that they are expanding their clinical-trial patient population next year from healthy individuals to people suffering from a host of chronic conditions.

“While they are part of our clinical trials, patients gain valuable insight in their own conditions. We also sometimes pick up underlying medical issues they were not even aware of,” says Michelle.

The 150 Farmovs staff members range from doctors and nurses, to technologists, medical writers, and managers. While not technically part of the university staff, they form a valued part of the Bloemfontein Campus community.

News Archive

Darwin lecture focuses on the genetic foundation of evolution
2009-05-22

 
The Department of Genetics at the University of the Free State (UFS) recently made their contribution to the story of life and survival by presenting two lectures on The genetic foundation of evolution. Prof. Johan Spies, Head of the Department of Genetics at the UFS discussed the variation that was created by mutations and how this variation was enhanced by re-combination. He also pointed out that these methods contributed relatively little to the gene pool of a species and that the expansion of the gene pool primarily took place by means of chromosome evolution. The latter also contributed to the creation of isolation mechanisms to prevent hybridism. He further emphasised the multitude of deviations of mendelian heredity, which contributed to more variation within a species.

Prof. Paul Grobler, Associate Professor from this department, next pointed out how natural selection played a role to form new species. He used various examples to indicate how the process took its course, for example, lactose intolerance. He also reported out that the man on the street mostly believed that Darwin with his theory of the survival of the fittest meant that the physically strongest species would survive. It was more a case of the one that could reproduce the fastest and the most, that would survive, he stated.

Present at the occasion were, from left front: Ms Letecia Jonker, student, Prof. Grobler, Ms Paula Spies, lecturer at the Department of Genetics and Ms Zurika Odendaal, junior lecturer at the Department of Genetics; back: Prof. Spies.
Photo: Stephen Collett

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