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23 January 2019 | Story Charlene Stanley | Photo Charlene Stanley
Michele Middle
Michelle Middle, CMO of Farmovs, looks forward to expanding their operations after the UFS acquired 100% shareholding in 2018.

In medical research, there are NO shortcuts.

The journey of a new medicine from lab to pharmacy shelf takes on average at least 10 years.

Michelle Middle’s journey from young medical graduate starting her first job at FARMOVS to becoming the company’s Chief Medical Officer, was more than twice that long. It was a journey that systematically and adequately equipped her to now Co-captain this flagship enterprise through its biggest challenge yet.

Michelle remembers how Farmovs started in 1974 as a research centre in the Department of Pharmacology. After graduating as medical doctor, she joined Farmovs in 1993, shortly before they moved to their current extensive facilities just south of the Sasol Library.

In 2000, international Clinical Research Organization (CRO) giant Parexel acquired a 70% shareholding, and the name changed to Farmovs-Parexel.

“Parexel really invested a lot in infrastructure and technology, bringing facilities here on par with the best in the world,” says Michelle.

Her own journey in medical research took her to George and later to the US and UK, where she held various international executive leadership positions in international companies.

When the UFS acquired a 100% shareholding in Farmovs earlier this year, she came full circle, as she returned to Bloemfontein to spearhead the expansion of patient studies in collaboration with the Faculty of Health Sciences.

“The opportunities we have here are really enormous,” says an excited Michelle.

“We are the only university in the country with this kind of infrastructure. Apart from our state-of-the-art bioanalytical lab, we also have facilities to accommodate close to 100 research participants. We now have 45 years’ experience in advanced medical research, plus established international clients. We can provide pharmaceutical companies with basically everything they need to develop new medicines.”

Another exciting development is that they are expanding their clinical-trial patient population next year from healthy individuals to people suffering from a host of chronic conditions.

“While they are part of our clinical trials, patients gain valuable insight in their own conditions. We also sometimes pick up underlying medical issues they were not even aware of,” says Michelle.

The 150 Farmovs staff members range from doctors and nurses, to technologists, medical writers, and managers. While not technically part of the university staff, they form a valued part of the Bloemfontein Campus community.

News Archive

Renowned forensic scientist speaks at the UFS
2014-04-02


Forensic science is about the truth. At the presentation delivered by Dr David Klatzow, were, from the left: Tinus Viljoen, lecturer in Forensic Genetics, Dr Klatzow and Laura Heathfield, also a lecturer in Forensic Genetics.
Photo: Leonie Bolleurs 

It is necessary for more research to be done in the field of forensic science in South Africa. This is according to Dr David Klatzow, well-known forensic scientist, during a lecture delivered at the University of the Free State (UFS) last week.

The university is offering, for the first time this year, a BSc degree in Forensic Science in the Department of Genetics. This three-year degree is, among others, directed at people working for the South African Police Service on crime scenes and on criminal cases in forensic laboratories. Students can also study up to PhD level, specialising in various forensic fields.

There is no accredited forensic laboratory in South Africa. “It is time to look differently at forensic science, and to deliver research papers on the subject. In light of the manner in which science is applied, we have to look differently at everything,” Dr Klatzow said.

Dr Klatzow praised the university for its chemistry-based course. “Chemistry is a strong basis for forensic science,” he said.

A paradigm shift in terms of forensic science is needed. Micro scratches on bullets, fingerprints, DNA, bite marks – all of these are forensic evidence that in the past led to people being wrongfully hanged. This evidence is not necessarily the alpha and omega of forensic science today. DNA, which seems to be the golden rule, can produce problems in itself. Because a person leaves DNA in his fingerprint, it is possible that DNA is transferred from one crime scene to another by forensic experts dusting for fingerprints. According to Dr Klatzow, this is only one of the problems that could be experienced with DNA evidence.

“No single set of forensic evidence is 100% effective or without problems. Rather approach the crime scene through a combination of evidence, by collecting fingerprints, DNA, etc. It is also very important to look at the context in which the events happened.

“A person sees what he expects to see. This causes huge problems in terms of forensic science. For example, if a criminal fits the profile of the perpetrator, it doesn’t follow that this specific criminal is the culprit. It isn’t what we don’t know that gives us trouble, it’s what we know that isn’t so,” Dr Klatzow said.

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