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23 January 2019 | Story Charlene Stanley | Photo Charlene Stanley
Michele Middle
Michelle Middle, CMO of Farmovs, looks forward to expanding their operations after the UFS acquired 100% shareholding in 2018.

In medical research, there are NO shortcuts.

The journey of a new medicine from lab to pharmacy shelf takes on average at least 10 years.

Michelle Middle’s journey from young medical graduate starting her first job at FARMOVS to becoming the company’s Chief Medical Officer, was more than twice that long. It was a journey that systematically and adequately equipped her to now Co-captain this flagship enterprise through its biggest challenge yet.

Michelle remembers how Farmovs started in 1974 as a research centre in the Department of Pharmacology. After graduating as medical doctor, she joined Farmovs in 1993, shortly before they moved to their current extensive facilities just south of the Sasol Library.

In 2000, international Clinical Research Organization (CRO) giant Parexel acquired a 70% shareholding, and the name changed to Farmovs-Parexel.

“Parexel really invested a lot in infrastructure and technology, bringing facilities here on par with the best in the world,” says Michelle.

Her own journey in medical research took her to George and later to the US and UK, where she held various international executive leadership positions in international companies.

When the UFS acquired a 100% shareholding in Farmovs earlier this year, she came full circle, as she returned to Bloemfontein to spearhead the expansion of patient studies in collaboration with the Faculty of Health Sciences.

“The opportunities we have here are really enormous,” says an excited Michelle.

“We are the only university in the country with this kind of infrastructure. Apart from our state-of-the-art bioanalytical lab, we also have facilities to accommodate close to 100 research participants. We now have 45 years’ experience in advanced medical research, plus established international clients. We can provide pharmaceutical companies with basically everything they need to develop new medicines.”

Another exciting development is that they are expanding their clinical-trial patient population next year from healthy individuals to people suffering from a host of chronic conditions.

“While they are part of our clinical trials, patients gain valuable insight in their own conditions. We also sometimes pick up underlying medical issues they were not even aware of,” says Michelle.

The 150 Farmovs staff members range from doctors and nurses, to technologists, medical writers, and managers. While not technically part of the university staff, they form a valued part of the Bloemfontein Campus community.

News Archive

Unconventional oil and gas extraction – study for Water Research Commission reveals possible impacts
2014-11-05

 

Photo: Legalplanet.org
The Centre for Environmental Management (CEM) at the University of the Free State (UFS) recently completed a three-year project for the Water Research Commission. The purpose was to develop an interactive vulnerability map and monitoring framework for unconventional oil and gas extraction (final report still to be published).

Due to the complexity of this field, a number of participants across different disciplines and universities were involved in this trans-disciplinary study. Contributors included the Departments of Sociology, Physics and Mathematical Statistics from the UFS, the University of Pretoria Natural Hazard Centre, Africa, as well as the Institute of Marine and Environmental Law from the University of Cape Town.

Unconventional oil and gas extraction, its related impacts and the management of this activity to ensure environmental protection, is a controversial issue in many countries worldwide. Since the extraction of oil and gas using unconventional techniques is an unprecedented activity in South Africa, the project focused on understanding this extraction process as well as hydraulic fracturing and identifying possible environmental and socio-economic impacts associated with this activity in the South African context. An understanding of the possible impacts could aid government during the development of policy aimed at protecting the environment.

The researchers subsequently identified indicators to develop an interactive vulnerability map for unconventional oil and gas in South Africa. The vulnerability map focuses on specific mapping themes, which include surface water, groundwater, vegetation, seismicity and socio-economics. In addition, the map provides information on the vulnerability of the specified mapping themes to unconventional gas extraction on a regional scale. This map is intended as a reconnaissance tool to inform decision-makers on areas where additional detail field work and assessments may be required. It can also be used during Environmental Impact Assessments and determining licensing conditions.

Lastly, a monitoring framework was developed, which describes monitoring requirements for specific entities – surface water, groundwater, vegetation, seismicity and socio-economics – for the different phases of unconventional oil and gas extraction. Such monitoring is an important part of environmental protection. It is especially important for South Africa to perform baseline monitoring before exploration starts to ensure that we will have reference conditions to identify what impact oil and gas extraction activities has on the biophysical and socio-economic environments.


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