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23 January 2019 | Story Charlene Stanley | Photo Charlene Stanley
Michele Middle
Michelle Middle, CMO of Farmovs, looks forward to expanding their operations after the UFS acquired 100% shareholding in 2018.

In medical research, there are NO shortcuts.

The journey of a new medicine from lab to pharmacy shelf takes on average at least 10 years.

Michelle Middle’s journey from young medical graduate starting her first job at FARMOVS to becoming the company’s Chief Medical Officer, was more than twice that long. It was a journey that systematically and adequately equipped her to now Co-captain this flagship enterprise through its biggest challenge yet.

Michelle remembers how Farmovs started in 1974 as a research centre in the Department of Pharmacology. After graduating as medical doctor, she joined Farmovs in 1993, shortly before they moved to their current extensive facilities just south of the Sasol Library.

In 2000, international Clinical Research Organization (CRO) giant Parexel acquired a 70% shareholding, and the name changed to Farmovs-Parexel.

“Parexel really invested a lot in infrastructure and technology, bringing facilities here on par with the best in the world,” says Michelle.

Her own journey in medical research took her to George and later to the US and UK, where she held various international executive leadership positions in international companies.

When the UFS acquired a 100% shareholding in Farmovs earlier this year, she came full circle, as she returned to Bloemfontein to spearhead the expansion of patient studies in collaboration with the Faculty of Health Sciences.

“The opportunities we have here are really enormous,” says an excited Michelle.

“We are the only university in the country with this kind of infrastructure. Apart from our state-of-the-art bioanalytical lab, we also have facilities to accommodate close to 100 research participants. We now have 45 years’ experience in advanced medical research, plus established international clients. We can provide pharmaceutical companies with basically everything they need to develop new medicines.”

Another exciting development is that they are expanding their clinical-trial patient population next year from healthy individuals to people suffering from a host of chronic conditions.

“While they are part of our clinical trials, patients gain valuable insight in their own conditions. We also sometimes pick up underlying medical issues they were not even aware of,” says Michelle.

The 150 Farmovs staff members range from doctors and nurses, to technologists, medical writers, and managers. While not technically part of the university staff, they form a valued part of the Bloemfontein Campus community.

News Archive

Dr Abdon Atangana cements his research globally by solving fractional calculus problem
2014-12-03

 

Dr Abdon Atangana

To publish 29 papers in respected international journals – and all of that in one year – is no mean feat. Postdoctoral researcher Abdon Atangana at the Institute for Groundwater Studies at the University of the Free State (UFS) reached this mark by October 2014, shortly before his 29th birthday.

His latest paper, ‘Modelling the Advancement of the Impurities and the Melted Oxygen concentration within the Scope of Fractional Calculus’, has been accepted for publication by the International Journal of Non-Linear Mechanics.

In previously-published research he solved a problem in the field of fractional calculus by introducing a fractional derivative called ‘Beta-derivative’ and its anti-derivative called ‘Atangana-Beta integral’, thereby cementing his research in this field.

Dr Atangana, originally from Cameroon, received his PhD in Geohydrology at the UFS in 2013. His research interests include:
• the theory of fractional calculus;
• modelling real world problems with fractional order derivatives;
• applications of fractional calculus;
• analytical methods for partial differential equations;
• analytical methods for ordinary differential equations;
• numerical methods for partial and ordinary differential equations; and
• iterative methods and uncertainties modelling.

Dr Atangana says that, “Applied mathematics can be regarded as the bridge between theory and practice. The use of mathematical tools for solving real world problems is as old as creation itself. As written in the book Genesis ‘And God saw the light, that it was good; and divided the light from the darkness’, the word division appears here as the well-known method of separation of variables, this method is usually employed to solve a class of linear partial differential equations”.

“A mathematical model is a depiction of a system using mathematical concepts and language. The procedure of developing a mathematical model is termed mathematical modelling. Mathematical models are used not only in natural sciences, but also in social sciences such as economics, psychology, sociology and political sciences. These models help to explain systems and to study the effects of different components, and to make predictions about behaviours.”

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