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23 January 2019 | Story Charlene Stanley | Photo Charlene Stanley
Michele Middle
Michelle Middle, CMO of Farmovs, looks forward to expanding their operations after the UFS acquired 100% shareholding in 2018.

In medical research, there are NO shortcuts.

The journey of a new medicine from lab to pharmacy shelf takes on average at least 10 years.

Michelle Middle’s journey from young medical graduate starting her first job at FARMOVS to becoming the company’s Chief Medical Officer, was more than twice that long. It was a journey that systematically and adequately equipped her to now Co-captain this flagship enterprise through its biggest challenge yet.

Michelle remembers how Farmovs started in 1974 as a research centre in the Department of Pharmacology. After graduating as medical doctor, she joined Farmovs in 1993, shortly before they moved to their current extensive facilities just south of the Sasol Library.

In 2000, international Clinical Research Organization (CRO) giant Parexel acquired a 70% shareholding, and the name changed to Farmovs-Parexel.

“Parexel really invested a lot in infrastructure and technology, bringing facilities here on par with the best in the world,” says Michelle.

Her own journey in medical research took her to George and later to the US and UK, where she held various international executive leadership positions in international companies.

When the UFS acquired a 100% shareholding in Farmovs earlier this year, she came full circle, as she returned to Bloemfontein to spearhead the expansion of patient studies in collaboration with the Faculty of Health Sciences.

“The opportunities we have here are really enormous,” says an excited Michelle.

“We are the only university in the country with this kind of infrastructure. Apart from our state-of-the-art bioanalytical lab, we also have facilities to accommodate close to 100 research participants. We now have 45 years’ experience in advanced medical research, plus established international clients. We can provide pharmaceutical companies with basically everything they need to develop new medicines.”

Another exciting development is that they are expanding their clinical-trial patient population next year from healthy individuals to people suffering from a host of chronic conditions.

“While they are part of our clinical trials, patients gain valuable insight in their own conditions. We also sometimes pick up underlying medical issues they were not even aware of,” says Michelle.

The 150 Farmovs staff members range from doctors and nurses, to technologists, medical writers, and managers. While not technically part of the university staff, they form a valued part of the Bloemfontein Campus community.

News Archive

The impact of personal care products on water resources in the Free State
2015-12-14

Jou-an Chen
Photo: Charl Devenish

Water is of the utmost importance in personal hygiene. Most people can hardly have a day go by without taking a shower in the morning and at night. However, it is this very habit that is increasingly polluting the water resources in South Africa.

Contaminants found in pharmaceutical and personal care products have been accumulating in water masses in recent years. These contaminants especially refer to hormones in medication, as well as colouring agents and fragrances used in soap, shampoo and body lotions.

“Little information and data are available on the prevalence of these contaminants, and on how high the level of pollution really is,” says Jou-an Chen, researcher in the Department of Microbial, Biochemical and Food Biotechnology at the UFS.

Her research particularly focuses on the prevalence and impact of those contaminants.

“Because these substances have not been properly investigated, we are not sure how widely it occurs and whether it is harmful to the environment. It was precisely the lack of information that has inspired me to investigate further.”

“If we could identify the contaminants and what it is doing to the environment, it could make a valuable contribution to directives on water quality standards.”


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