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23 January 2019 | Story Charlene Stanley | Photo Charlene Stanley
Michele Middle
Michelle Middle, CMO of Farmovs, looks forward to expanding their operations after the UFS acquired 100% shareholding in 2018.

In medical research, there are NO shortcuts.

The journey of a new medicine from lab to pharmacy shelf takes on average at least 10 years.

Michelle Middle’s journey from young medical graduate starting her first job at FARMOVS to becoming the company’s Chief Medical Officer, was more than twice that long. It was a journey that systematically and adequately equipped her to now Co-captain this flagship enterprise through its biggest challenge yet.

Michelle remembers how Farmovs started in 1974 as a research centre in the Department of Pharmacology. After graduating as medical doctor, she joined Farmovs in 1993, shortly before they moved to their current extensive facilities just south of the Sasol Library.

In 2000, international Clinical Research Organization (CRO) giant Parexel acquired a 70% shareholding, and the name changed to Farmovs-Parexel.

“Parexel really invested a lot in infrastructure and technology, bringing facilities here on par with the best in the world,” says Michelle.

Her own journey in medical research took her to George and later to the US and UK, where she held various international executive leadership positions in international companies.

When the UFS acquired a 100% shareholding in Farmovs earlier this year, she came full circle, as she returned to Bloemfontein to spearhead the expansion of patient studies in collaboration with the Faculty of Health Sciences.

“The opportunities we have here are really enormous,” says an excited Michelle.

“We are the only university in the country with this kind of infrastructure. Apart from our state-of-the-art bioanalytical lab, we also have facilities to accommodate close to 100 research participants. We now have 45 years’ experience in advanced medical research, plus established international clients. We can provide pharmaceutical companies with basically everything they need to develop new medicines.”

Another exciting development is that they are expanding their clinical-trial patient population next year from healthy individuals to people suffering from a host of chronic conditions.

“While they are part of our clinical trials, patients gain valuable insight in their own conditions. We also sometimes pick up underlying medical issues they were not even aware of,” says Michelle.

The 150 Farmovs staff members range from doctors and nurses, to technologists, medical writers, and managers. While not technically part of the university staff, they form a valued part of the Bloemfontein Campus community.

News Archive

Researcher wins prize for her work to reduce environmental pollution
2016-12-26

Description: Josepha Zielke Tags: Josepha Zielke 

Prof Danie Vermeulen, Dean of the Faculty of Natural
and Agricultural Sciences, and Josepha Zielke, a
PhD student at the Institute for Groundwater studies at the
University of the Free State.
Photo: Leonie Bolleurs

Josepha Zielke, a PhD student at the Institute for Groundwater Studies at the University of the Free State (UFS), received the prize for the best student presentation at the International Mine Water Association (IMWA) symposium in Leipzig, Germany, this year. Her paper was titled Fine Ash Leaching in Tailings Dams – An Impact on the Underlying Aquifers?
 
Zielke said: “It is an honour to receive this prize as a student. IMWA is a big association which allows you to establish a network with other scientists, to exchange opinions and ideas and to gain new inspiration for your own work. It was exciting and informative to hear about the research conducted around the world and to meet the researchers themselves.”
 
Born in Germany, Zielke always wanted to study overseas. During an exchange year in Grade 11, she visited South Africa. When she had to make a decision about in which country to complete her studies, South Africa was first choice as she was familiar with the people and the country.
 
Zielke joins leading institute on groundwater research in the country
She completed her BSc Hons in Geology at the Nelson Mandela Metropolitan University. After working for a year in exploration, she decided to focus her studies on water-related problems which  has been a growing issue, not only in South Africa, but in many places around the world. Zielke heard that the UFS Institute for Groundwater Studies was the leading institute on groundwater research in the country, and decided to join the university.
 
After completing her MSc research, An analysis of the geochemical weathering profile within a fine ash tailings dam, Mpumalanga, South Africa, Zielke started the research for her PhD project on groundwater pollution along a fault system in Mpumalanga.
 
Research adding value to the environment by reducing pollution
She explains the focus of her research: “Several production plants and mine waste facilities are located on or near these geological structures which could be a possible cause of ground and surface water pollution. With the aid of geophysical ground surveys (using electromagnetics and electrical resistivity tomography), aquifer and tracer tests, we are trying to determine where the pollution is coming from, how far it has been distributed and to model the potential risks.
 
“This research will add value to the environment by preventing or at least reducing pollution leaking into the environment. Industrial sites always have a negative footprint on the environment but at least we try and contain it by finding the cause of ground and surface water pollution. Thereafter we try and solve the pollution problem or at least mitigate the damage to prevent the spreading of ground and surface water pollution in the area.”

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