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23 January 2019 | Story Charlene Stanley | Photo Charlene Stanley
Michele Middle
Michelle Middle, CMO of Farmovs, looks forward to expanding their operations after the UFS acquired 100% shareholding in 2018.

In medical research, there are NO shortcuts.

The journey of a new medicine from lab to pharmacy shelf takes on average at least 10 years.

Michelle Middle’s journey from young medical graduate starting her first job at FARMOVS to becoming the company’s Chief Medical Officer, was more than twice that long. It was a journey that systematically and adequately equipped her to now Co-captain this flagship enterprise through its biggest challenge yet.

Michelle remembers how Farmovs started in 1974 as a research centre in the Department of Pharmacology. After graduating as medical doctor, she joined Farmovs in 1993, shortly before they moved to their current extensive facilities just south of the Sasol Library.

In 2000, international Clinical Research Organization (CRO) giant Parexel acquired a 70% shareholding, and the name changed to Farmovs-Parexel.

“Parexel really invested a lot in infrastructure and technology, bringing facilities here on par with the best in the world,” says Michelle.

Her own journey in medical research took her to George and later to the US and UK, where she held various international executive leadership positions in international companies.

When the UFS acquired a 100% shareholding in Farmovs earlier this year, she came full circle, as she returned to Bloemfontein to spearhead the expansion of patient studies in collaboration with the Faculty of Health Sciences.

“The opportunities we have here are really enormous,” says an excited Michelle.

“We are the only university in the country with this kind of infrastructure. Apart from our state-of-the-art bioanalytical lab, we also have facilities to accommodate close to 100 research participants. We now have 45 years’ experience in advanced medical research, plus established international clients. We can provide pharmaceutical companies with basically everything they need to develop new medicines.”

Another exciting development is that they are expanding their clinical-trial patient population next year from healthy individuals to people suffering from a host of chronic conditions.

“While they are part of our clinical trials, patients gain valuable insight in their own conditions. We also sometimes pick up underlying medical issues they were not even aware of,” says Michelle.

The 150 Farmovs staff members range from doctors and nurses, to technologists, medical writers, and managers. While not technically part of the university staff, they form a valued part of the Bloemfontein Campus community.

News Archive

From music to theology: Stats Unit valuable in research process
2017-02-23

Description: Prof Robert Schall Tags: Prof Robert Schall

Prof Schall, head of the UFS Statistical Consultation Unit
Photo: Leonie Bolleurs

Whether it is analysing data on church attendance, climate change in the Northern Cape or injuries among elite female hockey players, the Statistical Consultation Unit at the University of the Free State (UFS) can assist researchers from the planning of research to publication therof.

Many students and researchers think that the time to consult a statistician is after their research data has been collected. According to Prof Robert Schall, head of the unit, the most significant contribution a statistician can make to a research project is often during its planning. Preferably all researchers should consult the unit early in the research process.

Statistical consultation service free for postgraduates

The consultation unit, established in 2014 in the Department of Mathematical Statistics and Actuarial Science, provides support to all UFS researchers. This service is rendered to postgraduate students at no charge.

“The unit can make a contribution throughout the research process, from the planning of the research project, through the analysis of research data, up to the publication of the findings. I have been involved in projects where, for example, a few very simple changes to the design of a questionnaire would have saved the researcher and the statistician a lot of trouble. It will be beneficial for researchers to have their questionnaires and study proposals (where relevant), reviewed by a statistician,” Prof Schall said.

“The unit can make a contribution
throughout the research process,
from the planning of the research
project, through the analysis of
research data, up to the publication
of the findings.”

Fascinating research topics deliver fascinating data
The professor assisted in a study for the Department of Soil, Crop and Climate Sciences to determine whether rainfall in the Northern Cape had changed over the past 90 years, potentially indicating climate change.

Other interesting projects he has worked on came from the Department of Exercise and Sport Sciences. “Who will not be fascinated by data sets on aspects of rugby, cricket or even netball? One significant finding was a predictor of injury in elite female hockey players. The PhD student identified a pre-season test which predicted the occurrence of an in-season injury with 100% specificity and 100% sensitivity. The finding was quite surprising, and, if the results can be replicated, obviously would be useful in the prevention of injuries,” he said.

This is, of course, not an exhaustive list of projects the unit has worked on. “Not in my wildest dreams would I have expected to be involved in projects coming from the Faculty of Theology, or from the Odeion School of Music,” Prof Schall said.

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