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14 January 2019 | Story Eugene Seegers | Photo Anja Aucamp
Study Bug Bites Historian Early
Prof Corene de Wet, South Campus researcher, is a dedicated historian and educator.

From a childhood dream of being a historian, to a decades-long educator and double doctorate-holder, Prof Corene de Wet has led an eventful life. Realising that her undergrad qualification on its own would not get her a job, she completed the Higher Diploma in Education at the then Potchefstroom University for Christian Higher Education. However, “just to buy some time for myself,” she decided to study part-time while teaching in Winburg.

Prof De Wet calls it “being bitten by the part-time study bug.” By 1991, she had obtained her BEd (an honours degree at the time), MEd, and DEd degrees. In 1999, she graduated with a PhD in History. Today, Prof De Wet is still a research associate on our South Campus.

Tremendous milestones and mentors

Dr Lynette Jacobs, co-researcher on several projects, says, “Prof De Wet was the first woman to receive a full professorship in the Faculty of Education, and the first woman in the faculty to obtain an NRF rating. She received her professorship at a time when the academic world belonged to men. She outclassed her peers, rising head and shoulders above the crowd.”

Prof De Wet says her superhero is Prof Daniella Coetzee, South Campus Principal and long-time colleague. “Prof Coetzee is a brilliant academic and organiser. She makes every member of her staff feel special. I am ever thankful that she saw the need for a researcher on the South Campus and that she appointed me in this position,” says Prof De Wet.

“She is a seasoned academic who
still enjoys international recognition.”
—Dr Lynette Jacobs.

Generational history and work ethic

Although much has changed in education since her initial research, Prof De Wet believes that both her doctoral dissertations still bear scrutiny. Regarding the zeitgeist and its impact on the written history of a nation, Prof De Wet says, “We regularly hear many voices today who say that history must be ‘rewritten’. My thesis dealt with exactly that: How different generations of historians wrote histories influenced by the spirit of the time, or by textbooks, or by their own political or world views, or their philosophy on life. Thus, different generations interpret the same events differently.”

During a career spanning more than four decades, Prof De Wet has upheld a strong work ethic. This has enabled her to maintain her C-rating as an NRF researcher. “If one doesn’t dare, if you are too afraid of critique or failure, you won’t get anywhere in academia,” she says, adding, “Criticism is part of academic life. Therefore, take chances, and learn from healthy, constructive criticism.”

News Archive

Nanotechnology breakthrough at UFS
2010-08-19

 Ph.D students, Chantel Swart and Ntsoaki Leeuw


Scientists at the University of the Free State (UFS) made an important breakthrough in the use of nanotechnology in medical and biological research. The UFS team’s research has been accepted for publication by the internationally accredited Canadian Journal of Microbiology.

The UFS study dissected yeast cells exposed to over-used cooking oil by peeling microscopically thin layers off the yeast cells through the use of nanotechnology.

The yeast cells were enlarged thousands of times to study what was going on inside the cells, whilst at the same time establishing the chemical elements the cells are composed of. This was done by making microscopically small surgical incisions into the cell walls.

This groundbreaking research opens up a host of new uses for nanotechnology, as it was the first study ever in which biological cells were surgically manipulated and at the same time elemental analysis performed through nanotechnology. According to Prof. Lodewyk Kock, head of the Division Lipid Biotechnology at the UFS, the study has far reaching implications for biological and medical research.

The research was the result of collaboration between the Department of Microbial, Biochemical and Food Biotechnology, the Department of Physics (under the leadership of Prof. Hendrik Swart) and the Centre for Microscopy (under the leadership of Prof.Pieter van Wyk).

Two Ph.D. students, Chantel Swart and Ntsoaki Leeuw, overseen by professors Kock and Van Wyk, managed to successfully prepare yeast that was exposed to over-used cooking oil (used for deep frying of food) for this first ever method of nanotechnological research.

According to Prof. Kock, a single yeast cell is approximately 5 micrometres long. “A micrometre is one millionth of a metre – in laymen’s terms, even less than the diameter of a single hair – and completely invisible to the human eye.”

Through the use of nanotechnology, the chemical composition of the surface of the yeast cells could be established by making a surgical incision into the surface. The cells could be peeled off in layers of approximately three (3) nanometres at a time to establish the effect of the oil on the yeast cell’s composition. A nanometre is one thousandth of a micrometre.

Each cell was enlarged by between 40 000 and 50 000 times. This was done by using the Department of Physics’ PHI700 Scanning Auger Nanoprobe linked to a Scanning Electron Microscope and Argon-etching. Under the guidance of Prof. Swart, Mss. Swart en Leeuw could dissect the surfaces of yeast cells exposed to over-used cooking oil. 

The study noted wart like outgrowths - some only a few nanometres in diameter – on the cell surfaces. Research concluded that these outgrowths were caused by the oil. The exposure to the oil also drastically hampered the growth of the yeast cells. (See figure 1)  

Researchers worldwide have warned about the over-usage of cooking oil for deep frying of food, as it can be linked to the cause of diseases like cancer. The over-usage of cooking oil in the preparation of food is therefore strictly regulated by laws worldwide.

The UFS-research doesn’t only show that over-used cooking oil is harmful to micro-organisms like yeast, but also suggests how nanotechnology can be used in biological and medical research on, amongst others, cancer cells.

 

Figure 1. Yeast cells exposed to over-used cooking oil. Wart like protuberances/ outgrowths (WP) is clearly visible on the surfaces of the elongated yeast cells. With the use of nanotechnology, it is possible to peel off the warts – some with a diameter of only a few nanometres – in layers only a few nanometres thick. At the same time, the 3D-structure of the warts as well as its chemical composition can be established.  

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za  
18 August 2010
 

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