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14 November 2019 | Story Charlene Stanley | Photo Supplied
DIABETES read more
The modern clinical research facilities at FARMOVS where the two ground breaking diabetes studies will be conducted.

Diabetes is no longer seen simply as a disease, but as a worldwide epidemic, with alarming increases recorded in both developed and developing countries over the past few years.

About 3,5 million South Africans have diabetes, and many more are unaware that they have it. 

The FARMOVS clinical research facility on the Bloemfontein Campus of the University of the Free State is currently involved in two exciting research studies that could lead to the development of medication for diabetes sufferers burdened by some of its most common complications.

Diabetes in a nutshell

Diabetes is a group of diseases where the sugar (glucose) levels in the blood are too high. 

In diabetes mellitus (DM), the high blood-sugar levels are caused by the body not being able to control the blood-sugar levels properly, because of the body’s inability to produce or use insulin. Insulin is a hormone produced by the pancreas and lowers the blood-sugar levels by helping to move the sugar from the blood into the body cells where the sugar is used as a source of energy.

Type 1 DM is often diagnosed in children or teenagers and occurs when the pancreas does not produce any insulin. Type 2 DM occurs when the pancreas does not make enough insulin, or if the body can no longer use the insulin properly; this is often associated with poor lifestyle choices. Where this type of diabetes used to develop primarily in adults of 40 years and older, it is nowadays not uncommon for children to be diagnosed with it.


It is essential that people who are displaying one or more of the risk factors go for screening. This includes a search Physician at FARMOVS. “If DM is detected early enough, up to 90% of people don’t have to use medication but can address it through changes to their diet and exercise programmes.”

High blood-sugar levels essentially damage the blood vessels, which can lead to long-term implications for a person’s heart, kidneys, eyes, and blood circulation. 
The international studies that FARMOVS forms part of, aim to develop treatments for two of the most common secondary conditions that develop as a result of diabetes. 

Diabetic gastroparesis study

A sufferer’s intestines often don’t function properly due to the damage diabetes causes to the nerves which helps the stomach to empty properly; a condition called gastroparesis. Alleviating this condition, typically marked by abdominal pain, bloating, nausea, vomiting, and early satiety (feeling full after eating only a small amount of food), is the aim of one of the studies.

Diabetic impaired kidney function study

A second research study focuses on developing medication that will have a protective effect on a diabetic’s kidneys.  Although nothing can be done to reverse kidney damage, it is hoped that the treatment will slow down kidney degradation.

Focus on prevention

“Both of these studies are aimed at giving diabetics an increased quality of life, and by no means constitute a cure for their condition,” says Dr Van Jaarsveld.
 “The solution lies in combining the correct and committed use of medication with a decreased calorie intake and an increase in exercise – even if it’s just 30 minutes three times a week.”

Value of educating sufferers

A major benefit for participants in the FARMOVS diabetes research trials, is that they gain valuable insight in their own condition.
Diabetes has been called the ‘silent disease’, since sufferers initially have no symptoms.  For that reason, when the average patient is diagnosed with the disease, he/she already has had it for 10 years.   

For me, diabetes is such a sad disease – especially when you see patients with amputated body parts, knowing that it could have been prevented. It is really up to each individual to take responsibility for their own health,” Dr Van Jaarsveld concludes.

Diabetics who are interested in becoming part of the research studies can register online at www.farmovs.com, or contact FARMOVS at +27 51 410 3111.

News Archive

Bloemfontein's quality of tap water compares very favourably with bottled water
2009-08-04

The quality of the drinking water of five suburbs in Bloemfontein is at least as good as or better than bottled water. This is the result of a standard and chemical bacterial analysis done by the University of the Free State’s (UFS) Centre for Environmental Management in collaboration with the Institute for Groundwater Studies (IGS).

Five samples were taken from tap water sources in the suburbs of Universitas, Brandwag, Bain’s Vlei, Langenhoven Park and Bayswater and 15 samples were taken of different brands of still and unflavoured bottled water. The samples were analysed at the laboratory of the IGS, while the interpretation of the analysis was done by the Centre for Environmental Management.

“We wanted to evaluate the difference in quality for human consumption between tap water and that of the different brands of bottled water,” said Prof. Maitland Seaman, Head of the Centre for Environmental Management.

“With the exception of two samples produced by multinational companies at their plants in South Africa, the different brands of bottled water used for the study were produced by South African companies, including a local small-scale Bloemfontein producer,” said Prof. Seaman.

According to the labels, the sources of the water vary from pure spring water, to partial reverse osmosis (as an aid to standardise salt, i.e. mineral, content), to only reverse osmosis (to remove salts). (Reverse osmosis is a process in which water is forced under pressure through a pipe with minute pores through which water passes but no – or very low concentrations of – salts pass.)

According to Prof. Seaman, the analysis revealed some interesting findings, such as:

• It is generally accepted that drinking water should have an acceptable level of salt content, as the body needs salts. Most mineral contents were relatively higher in the tap water samples than the bottled water samples and were very much within the acceptable range of drinkable water quality. One of the bottled samples, however, had a very low mineral content, as the water was produced by reverse osmosis, as stated on the bottle. While reverse osmosis is used by various producers, most producers use it as an aid, not as a single method to remove nearly all the salts. Drinking only such water over a prolonged period may probably have a negative effect on the human physiology.

• The pH values of the tap water samples (8,12–8,40) were found to be slightly higher (slightly alkaline), like in all south-eastern Free State rivers (from where the water is sourced) than the pH of most of the bottled water samples, most of which are sourced and/or treated in other areas. Two brands of bottled water were found to have relatively low pH levels (both 4,5, i.e. acidic) as indicated on their bottles and as confirmed by the IGS analysis. The health implication of this range of pH is not significant.

• The analysis showed differences in the mineral content given on the labels of most of the water bottles compared to that found by IGS analysis. The possibility of seasonal fluctuation in content, depending on various factors, is expected and most of the bottling companies also indicate this on their labels. What was a rather interesting finding was that two pairs of bottled water brands claimed exactly the same mineral content but appeared under different brand names and were also priced differently. In each case, one of the pair was a well-known house brand, and the other obviously the original producer. In one of these paired cases, the house brand stated that the water was spring water, while the other (identical) “original” brand stated that it was spring water treated by reverse osmosis and oxygen-enriched.

• Nitrate (NO3) levels were uniformly low except in one bottled sample, suggesting a low (non-threatening) level of organic pollution in the source water. Otherwise, none of the water showed any sign of pollution.

• The bacterial analysis confirmed the absence of any traces of coliforms or E.coli in any of the samples, as was also indicated by the bottling companies. This is very reassuring. What is not known is how all these waters were sterilised, which could be anything from irradiation to chlorine or ozone treatment.

• The price of the different brands of bottled water, each containing 500 ml of still water, ranged between R3,99 and R8,99, with R5,03 being the average price. A comparison between the least expensive and the most expensive bottles of water indicated no significant difference in quality. In fact, discrepancies were observed in the most expensive bottle in that the amount of Calcium (Ca) claimed to be present in it was found to be significantly different from what the analysis indicated (29,6 mg/l versus 0,92 mg/l). The alkalinity (CaCO3 mg/l) indicated on the bottle was also found to differ considerably (83 mg/l versus 9,4 mg/l). The concentration of Total Dissolved Salts (TDS) was not given on the product.

“The preference for bottled water as compared to Bloemfontein’s tap water from a qualitative perspective as well as the price discrepancy is unjustifiable. The environmental footprint of bottled water is also large. Sourcing, treating, bottling, packaging and transporting, to mention but a few of the steps involved in the processing of bottled water, entail a huge carbon footprint, as well as a large water footprint, because it also requires water for treating and rinsing to process bottled water,” said Prof. Seaman.

Media Release
Lacea Loader
Deputy Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
3 August 2009

 

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