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14 November 2019 | Story Charlene Stanley | Photo Supplied
DIABETES read more
The modern clinical research facilities at FARMOVS where the two ground breaking diabetes studies will be conducted.

Diabetes is no longer seen simply as a disease, but as a worldwide epidemic, with alarming increases recorded in both developed and developing countries over the past few years.

About 3,5 million South Africans have diabetes, and many more are unaware that they have it. 

The FARMOVS clinical research facility on the Bloemfontein Campus of the University of the Free State is currently involved in two exciting research studies that could lead to the development of medication for diabetes sufferers burdened by some of its most common complications.

Diabetes in a nutshell

Diabetes is a group of diseases where the sugar (glucose) levels in the blood are too high. 

In diabetes mellitus (DM), the high blood-sugar levels are caused by the body not being able to control the blood-sugar levels properly, because of the body’s inability to produce or use insulin. Insulin is a hormone produced by the pancreas and lowers the blood-sugar levels by helping to move the sugar from the blood into the body cells where the sugar is used as a source of energy.

Type 1 DM is often diagnosed in children or teenagers and occurs when the pancreas does not produce any insulin. Type 2 DM occurs when the pancreas does not make enough insulin, or if the body can no longer use the insulin properly; this is often associated with poor lifestyle choices. Where this type of diabetes used to develop primarily in adults of 40 years and older, it is nowadays not uncommon for children to be diagnosed with it.


It is essential that people who are displaying one or more of the risk factors go for screening. This includes a search Physician at FARMOVS. “If DM is detected early enough, up to 90% of people don’t have to use medication but can address it through changes to their diet and exercise programmes.”

High blood-sugar levels essentially damage the blood vessels, which can lead to long-term implications for a person’s heart, kidneys, eyes, and blood circulation. 
The international studies that FARMOVS forms part of, aim to develop treatments for two of the most common secondary conditions that develop as a result of diabetes. 

Diabetic gastroparesis study

A sufferer’s intestines often don’t function properly due to the damage diabetes causes to the nerves which helps the stomach to empty properly; a condition called gastroparesis. Alleviating this condition, typically marked by abdominal pain, bloating, nausea, vomiting, and early satiety (feeling full after eating only a small amount of food), is the aim of one of the studies.

Diabetic impaired kidney function study

A second research study focuses on developing medication that will have a protective effect on a diabetic’s kidneys.  Although nothing can be done to reverse kidney damage, it is hoped that the treatment will slow down kidney degradation.

Focus on prevention

“Both of these studies are aimed at giving diabetics an increased quality of life, and by no means constitute a cure for their condition,” says Dr Van Jaarsveld.
 “The solution lies in combining the correct and committed use of medication with a decreased calorie intake and an increase in exercise – even if it’s just 30 minutes three times a week.”

Value of educating sufferers

A major benefit for participants in the FARMOVS diabetes research trials, is that they gain valuable insight in their own condition.
Diabetes has been called the ‘silent disease’, since sufferers initially have no symptoms.  For that reason, when the average patient is diagnosed with the disease, he/she already has had it for 10 years.   

For me, diabetes is such a sad disease – especially when you see patients with amputated body parts, knowing that it could have been prevented. It is really up to each individual to take responsibility for their own health,” Dr Van Jaarsveld concludes.

Diabetics who are interested in becoming part of the research studies can register online at www.farmovs.com, or contact FARMOVS at +27 51 410 3111.

News Archive

Inaugural lecture: Prof. Phillipe Burger
2007-11-26

 

Attending the lecture were, from the left: Prof. Tienie Crous (Dean of the Faculty of Economic and Management Sciences at the UFS), Prof. Phillipe Burger (Departmental Chairperson of the Department of Economics at the UFS), and Prof. Frederick Fourie (Rector and Vice-Chancellor of the UFS).
Photo: Stephen Collet

 
A summary of an inaugural lecture presented by Prof. Phillipe Burger on the topic: “The ups and downs of the South African Economy: Rough seas or smooth sailing?”

South African business cycle shows reduction in volatility

Better monetary policy and improvements in the financial sector that place less liquidity constraints on individuals is one of the main reasons for the reduction in the volatility of the South African economy. The improvement in access to the financial sector also enables individuals to manage their debt better.

These are some of the findings in an analysis on the volatility of the South African business cycle done by Prof. Philippe Burger, Departmental Chairperson of the University of the Free State’s (UFS) Department of Economics.

Prof. Burger delivered his inaugural lecture last night (22 November 2007) on the Main Campus in Bloemfontein on the topic “The ups and downs of the South African Economy: Rough seas or smooth sailing?”

In his lecture, Prof. Burger emphasised a few key aspects of the South African business cycle and indicated how it changed during the periods 1960-1976, 1976-1994 en 1994-2006.

With the Gross Domestic Product (GDP) as an indicator of the business cycle, the analysis identified the variables that showed the highest correlation with the GDP. During the periods 1976-1994 and 1994-2006, these included durable consumption, manufacturing investment, private sector investment, as well as investment in machinery and non-residential buildings. Other variables that also show a high correlation with the GDP are imports, non-durable consumption, investment in the financial services sector, investment by general government, as well as investment in residential buildings.

Prof. Burger’s analysis also shows that changes in durable consumption, investment in the manufacturing sector, investment in the private sector, as well as investment in non-residential buildings preceded changes in the GDP. If changes in a variable such as durable consumption precede changes in the GDP, it is an indication that durable consumption is one of the drivers of the business cycle. The up or down swing of durable consumption may, in other words, just as well contribute to an up or down swing in the business cycle.

A surprising finding of the analysis is the particularly strong role durable consumption has played in the business cycle since 1994. This finding is especially surprising due to the fact that durable consumption only constitutes about 12% of the total household consumption.

A further surprising finding is the particularly small role exports have been playing since 1960 as a driver of the business cycle. In South Africa it is still generally accepted that exports are one of the most important drivers of the business cycle. It is generally accepted that, should the business cycles of South Africa’s most important trade partners show an upward phase; these partners will purchase more from South Africa. This increase in exports will contribute to the South African economy moving upward. Prof. Burger’s analyses shows, however, that exports have generally never fulfil this role.

Over and above the identification of the drivers of the South African business cycle, Prof. Burger’s analysis also investigated the volatility of the business cycle.

When the periods 1976-1994 and 1994-2006 are compared, the analysis shows that the volatility of the business cycle has reduced since 1994 with more than half. The reduction in volatility can be traced to the reduction in the volatility of household consumption (especially durables and services), as well as a reduction in the volatility of investment in machinery, non-residential buildings and transport equipment. The last three coincide with the general reduction in the volatility of investment in the manufacturing sector. Investment in sectors such as electricity and transport (not to be confused with investment in transport equipment by various sectors) which are strongly dominated by the government, did not contribute to the decrease in volatility.

In his analysis, Prof. Burger supplies reasons for the reduction in volatility. One of the explanations is the reduction in the shocks affecting the economy – especially in the South African context. Another explanation is the application of an improved monetary policy by the South African Reserve Bank since the mid 1990’s. A third explanation is the better access to liquidity and credit since the mid 1990’s, which enables the better management of household finance and the absorption of financial shocks.

A further reason which contributed to the reduction in volatility in countries such as the United States of America’s business cycle is better inventory management. While the volatility of inventory in South Africa has also reduced there is, according to Prof. Burger, little proof that better inventory management contributed to the reduction in volatility of the GDP.

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